Sigvotatug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:44:32 GMT 2023` Edited by `admin` on `Sat Dec 16 15:44:32 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	ZD7KM155DD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Sigvotatug

Common Name

English

Immunoglobulin G1, anti-(human integrin β6) (human-Mus musculus monoclonal h2A2 γ1-chain), disulfide with human-Mus musculus monoclonal h2A2 κ-chain, dimer

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens ITGB6 (integrin subunit beta 6)], humanized monoclonal antibody

Common Name

English

sigvotatug [INN]

Common Name

English

Gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV1-46*01 (79.6%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01,G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2

Common Name

English

Code System Code Type Description

CAS

2764774-90-3

Created by admin on Sat Dec 16 15:44:32 GMT 2023 , Edited by admin on Sat Dec 16 15:44:32 GMT 2023

PRIMARY

FDA UNII

ZD7KM155DD

Created by admin on Sat Dec 16 15:44:32 GMT 2023 , Edited by admin on Sat Dec 16 15:44:32 GMT 2023

PRIMARY

INN

12758

Created by admin on Sat Dec 16 15:44:32 GMT 2023 , Edited by admin on Sat Dec 16 15:44:32 GMT 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_366	2_424
2_260	2_320
2_219	4_214
2_143	2_199
2_22	2_96
1_366	1_424
1_260	1_320
1_228	2_228
1_225	2_225
1_219	3_214
1_143	1_199
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					C3QS75G3YQ

INTEGRIN BETA-6

TARGET->LIGAND

Amount:


					QX0ONY0O9T

Sigvotatug vedotin

CONJUGATE -> PARENT

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL