U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H3NO
Molecular Weight 57.0513
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYACETONITRILE

SMILES

OCC#N

InChI

InChIKey=LTYRAPJYLUPLCI-UHFFFAOYSA-N
InChI=1S/C2H3NO/c3-1-2-4/h4H,2H2

HIDE SMILES / InChI

Molecular Formula C2H3NO
Molecular Weight 57.0513
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.
2007-09-14
New six-site acetonitrile model for simulations of liquid acetonitrile and its aqueous mixtures.
2007-09
Liquid chromatography-tandem mass spectrometric assays for salinomycin in mouse plasma, liver, brain and small intestinal contents and in OptiMEM cell culture medium.
2007-08-15
HPLC method for the determination of carboplatin and paclitaxel with cremophorEL in an amphiphilic polymer matrix.
2007-08-15
Observation of glycine zipper and unanticipated occurrence of ambidextrous helices in the crystal structure of a chiral undecapeptide.
2007-08-01
Enantioselective resolution of thyroxine hormone by high-performance liquid chromatography utilizing a highly fluorescent chiral tagging reagent.
2007-08
Development of an ultra-performance liquid chromatography-mass spectrometry method for the detection of lipophilic marine toxins.
2007-07-20
Homolog separation, a necessity for the proper identification of fungal metabolites.
2007-07-13
Simultaneous quantification of cyclophosphamide and its active metabolite 4-hydroxycyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-MS/MS).
2007-07-01
Determination of linezolid in growth media by high-performance liquid chromatography with on-line extraction.
2007-07-01
An unexpected observation concerning the effect of anionic additives on the retention behavior of basic drugs and peptides in reversed-phase liquid chromatography.
2007-06-22
Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: application to pharmacokinetic studies.
2007-06-01
Ultrafast proton transfer to solvent: molecularity and intermediates from solvation- and diffusion-controlled regimes.
2007-05-02
Validation of HPLC method for determination of atorvastatin in tablets and for monitoring stability in solid phase.
2007-04-19
Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection.
2007-03-22
Quantitative structure-retention relationships of pesticides in reversed-phase high-performance liquid chromatography.
2007-01-23
[Isolation and preparation of flavonoids from the leaves of Nelumbo nucifera Gaertn by preparative reversed-phase high performance liquid chromatography].
2007-01
Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis.
2007-01
Measurement and pharmacokinetic study of plumbagin in a conscious freely moving rat using liquid chromatography/tandem mass spectrometry.
2006-11-21
[Simultaneous determination of residues of 12 amide herbicides in soybeans by high performance liquid chromatography].
2006-11
A green method for the electroorganic synthesis of new 1,3-Indandione derivatives.
2006-10
Microwave-assisted extraction through an aqueous medium and simultaneous cleanup by partition on hexane for determining pesticides in agricultural soils by gas chromatography: a critical study.
2006-09-25
Rapid method for the determination of 16 organochlorine pesticides in sesame seeds by microwave-assisted extraction and analysis of extracts by gas chromatography-mass spectrometry.
2006-09-15
Quantitative determination of four constituents of Tinospora sps. by a reversed-phase HPLC-UV-DAD method. Broad-based studies revealing variation in content of four secondary metabolites in the plant from different eco-geographical regions of India.
2006-09
Pharmacokinetic study of p-coumaric acid in mouse after oral administration of extract of Ananas comosus L. leaves.
2006-09
An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection.
2006-08-19
Determination and levels of the biocide ortho-phenylphenol in canned beers from different countries.
2006-08-09
Development of a liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI MS/MS) method for the quantification of bioactive substances present in olive oil mill wastewaters.
2006-07-28
Chemical fingerprinting of Shexiang Baoxin Pill and simultaneous determination of its major constituents by HPLC with evaporative light scattering detection and electrospray mass spectrometric detection.
2006-07
Limitations of porous graphitic carbon as stationary phase material in the determination of catecholamines.
2006-06-30
Development and validation of a quantitative assay for the measurement of two HIV-fusion inhibitors, enfuvirtide and tifuvirtide, and one metabolite of enfuvirtide (M-20) in human plasma by liquid chromatography-tandem mass spectrometry.
2006-06-06
Determination of olanzapine in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
2006-06
Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction.
2006-04-11
Determination of eleutheroside E and eleutheroside B in rat plasma and tissue by high-performance liquid chromatography using solid-phase extraction and photodiode array detection.
2006-04
Application of a fast high-performance liquid chromatography method for simultaneous determination of furanic compounds and glucosylisomaltol in breakfast cereals.
2006-03-04
LC-ESI-MSD fast determination of residual mitomycin C in hen aqueous humour after corneal refractive surgery.
2006-01-23
Use of the land snail Helix aspersa as sentinel organism for monitoring ecotoxicologic effects of urban pollution: an integrated approach.
2006-01
Easy determination of the addition of soybean proteins to heat-processed meat products prepared with turkey meat or pork-turkey meat blends that could also contain milk proteins.
2005-12
Isolation and determination of ginsenosides in American ginseng leaves and root extracts by LC-MS.
2005-12
Liquid-vapor interfaces of water-acetonitrile mixtures of varying composition.
2005-11-08
Multiresidue analysis of pesticides in soil by gas chromatography with nitrogen-phosphorus detection and gas chromatography mass spectrometry.
2005-10-05
Simultaneous quantification of different cyclodextrins and Gantrez by HPLC with evaporative light scattering detection.
2005-09-15
Preparation and evaluation of uniform-sized molecularly imprinted polymer beads used for the separation of sulfamethazine.
2005-09
Solvation of tetraalkylammonium chlorides in acetonitrile-water mixtures: mass spectrometry and molecular dynamics simulations.
2005-07-11
Determination of midazolam and its major metabolite 1'-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children.
2005-07-05
Binding behaviour and conformational properties of globular proteins in the presence of immobilised non-polar ligands used in reversed-phase liquid chromatography.
2005-06-24
Monte Carlo simulations of the solution structure of simple alcohols in water-acetonitrile mixtures.
2005-03-31
Radical-mediated carboxylation of alkyl iodides with [11C]carbon monoxide in solvent mixtures.
2005-03-18
HPLC method for the determination and pharmacokinetic studies on puerarin in cerebral ischemia reperfusion rat plasma after intravenous administration of puerariae radix isoflavone.
2005-02-23
The rapid determination of sideroxylonals in Eucalyptus foliage by extraction with sonication followed by HPLC.
2005-02-04
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:29:49 GMT 2025
Edited
by admin
on Mon Mar 31 19:29:49 GMT 2025
Record UNII
ZCI474BE63
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLYCOLONITRILE
HSDB  
Preferred Name English
HYDROXYACETONITRILE
Systematic Name English
GLYCOLIC NITRILE
Common Name English
FORMALDEHYDE CYANOHYDRIN
Common Name English
ACETONITRILE, 2-HYDROXY-
Systematic Name English
CYANOMETHANOL
Systematic Name English
.ALPHA.-HYDROXYMETHYLCYANIDE
Common Name English
2-HYDROXYETHANENITRILE
Systematic Name English
NSC-1790
Code English
GLYCOLLONITRILE
Common Name English
GLYCOLONITRILE [HSDB]
Common Name English
METHYLENE CYANOHYDRIN
Systematic Name English
HYDROXYMETHYL CYANIDE
Systematic Name English
Code System Code Type Description
CHEBI
137685
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
FDA UNII
ZCI474BE63
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
NSC
1790
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
HSDB
2123
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
CHEBI
29308
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
WIKIPEDIA
Glycolonitrile
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
PUBCHEM
7857
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
EPA CompTox
DTXSID3025417
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
CAS
107-16-4
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY
ECHA (EC/EINECS)
203-469-1
Created by admin on Mon Mar 31 19:29:49 GMT 2025 , Edited by admin on Mon Mar 31 19:29:49 GMT 2025
PRIMARY