Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H7NO |
| Molecular Weight | 73.0938 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)CN
InChI
InChIKey=BCDGQXUMWHRQCB-UHFFFAOYSA-N
InChI=1S/C3H7NO/c1-3(5)2-4/h2,4H2,1H3
| Molecular Formula | C3H7NO |
| Molecular Weight | 73.0938 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. | 2010-12-10 |
|
| Acetyl radical production by the methylglyoxal-peroxynitrite system: a possible route for L-lysine acetylation. | 2010-11-15 |
|
| A small molecule that mimics the metabolic activity of copper-containing amine oxidases (CuAOs) toward physiological mono- and polyamines. | 2010-08-21 |
|
| Effects of capecitabine and celecoxib in experimental pancreatic cancer. | 2010 |
|
| Aminoacetone as the penultimate precursor to the antitumor agent azinomycin A. | 2009-09-03 |
|
| Highly thermostable L-threonine dehydrogenase from the hyperthermophilic archaeon Thermococcus kodakaraensis. | 2009-07 |
|
| A fluorometric high-performance liquid chromatography procedure for simultaneous determination of methylamine and aminoacetone in blood and tissues. | 2009-01-01 |
|
| Salt stress-induced alterations in the root proteome of barley genotypes with contrasting response towards salinity. | 2009 |
|
| d -Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis. | 2009 |
|
| Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death to insulin-producing RINm5f cells. | 2008-09 |
|
| Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors. | 2008-09 |
|
| Identification and monitoring of intermediates and products in the acrylamide pathway using online analysis. | 2008-08-13 |
|
| Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. | 2008-07 |
|
| The contribution of cerebral vascular semicarbazide-sensitive amine oxidase to cerebral amyloid angiopathy in Alzheimer's disease. | 2008-04 |
|
| N-methyl-N-phenylaminomethyl 2-naphthyl ketone: an X-ray diffraction and density functional theory study. | 2008-03 |
|
| Evidence for in vivo scavenging by aminoguanidine of formaldehyde produced via semicarbazide-sensitive amine oxidase-mediated deamination. | 2007-09 |
|
| First aminoacetone chelate: [Co(tren){NH2CH2C(O)CH3}]3+-a substrate binding and activation model for zinc(II)-dependent 5-aminolaevulinic acid dehydratase. | 2007-08-14 |
|
| Can ageing be prevented by dietary restriction? | 2007-02 |
|
| Catalytic transfer hydrogenation with terdentate CNN ruthenium complexes: the influence of the base. | 2007 |
|
| Effect of aldehydes derived from oxidative deamination and oxidative stress on beta-amyloid aggregation; pathological implications to Alzheimer's disease. | 2007 |
|
| Renalase, a catecholamine-metabolising enzyme? | 2007 |
|
| Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis. | 2006-12 |
|
| Diabetes and semicarbazide-sensitive amine oxidase (SSAO) activity: a review. | 2006-06-27 |
|
| Trace determination of 1-aminopropanone, a potential marker for wastewater contamination by liquid chromatography and atmospheric pressure chemical ionization-mass spectrometry. | 2006-02 |
|
| The dual face of endogenous alpha-aminoketones: pro-oxidizing metabolic weapons. | 2006-01-31 |
|
| A novel HPLC procedure for detection and quantification of aminoacetone, a precursor of methylglyoxal, in biological samples. | 2005-09-25 |
|
| Biphasic enantioselective olefin epoxidation using Tropos dibenzoazepinium catalysts. | 2005-07-22 |
|
| D-lactate metabolism in starved Octopus ocellatus. | 2005-06-01 |
|
| Aminoacetone induces oxidative modification to human plasma ceruloplasmin. | 2005-04 |
|
| Developmental profiles of 5-aminolevulinate, porphobilinogen and porphobilinogen synthase activity in Pieris brassicae related to the synthesis of the bilin-binding protein. | 2005-02 |
|
| Aminoacetone induces iron-mediated oxidative damage to isolated rat liver mitochondria. | 2004-10-15 |
|
| Semicarbazide-sensitive amine oxidase: current status and perspectives. | 2004-05 |
|
| Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice. | 2004-04 |
|
| Selective inhibitors of membrane-bound semicarbazide-sensitive amine oxidase (SSAO) activity in mammalian tissues. | 2004-01 |
|
| Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do. | 2004-01 |
|
| Thiosugar nucleosides. Synthesis and biological activity of 1,3,4-thiadiazole, thiazoline and thiourea derivatives of 5-thio-D-glucose. | 2004 |
|
| Aminoacetone induces loss of ferritin ferroxidase and iron uptake activities. | 2003-10 |
|
| Production of 5-aminolevulinic acid by an Escherichia coli aminolevulinate dehydratase mutant that overproduces Rhodobacter sphaeroides aminolevulinate synthase. | 2003-10 |
|
| Physiological and pathological implications of semicarbazide-sensitive amine oxidase. | 2003-04-11 |
|
| Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. | 2002-10-04 |
|
| The human L-threonine 3-dehydrogenase gene is an expressed pseudogene. | 2002-10-02 |
|
| Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in atherogenesis in KKAy diabetic mice fed with high cholesterol diet. | 2002-09 |
|
| Molecular cloning and tissue distribution of mammalian L-threonine 3-dehydrogenases. | 2002-06-25 |
|
| Inhibition and regulation of rat liver L-threonine dehydrogenase by different fatty acids and their derivatives. | 2001-11-07 |
|
| Aerobic oxidation of aminoacetone, a threonine catabolite: iron catalysis and coupled iron release from ferritin. | 2001-09 |
|
| Determination of 1-aminopropan-2-one, a dissolved sewage component, in water samples. | 2001-04 |
|
| 2-Bromoethylamine as a potent selective suicide inhibitor for semicarbazide-sensitive amine oxidase. | 2001-03-15 |
|
| Oxidative DNA damage induced by aminoacetone, an amino acid metabolite. | 1999-05-01 |
|
| Interaction between L-threonine dehydrogenase and aminoacetone synthetase and mechanism of aminoacetone production. | 1986-12-15 |
|
| [Effect of the pH value on the dissociation of the aminoketones delta-aminolevulinic acid and aminoacetone by extraction with ether and dichlormethane]. | 1981 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:04:55 GMT 2025
by
admin
on
Mon Mar 31 19:04:55 GMT 2025
|
| Record UNII |
ZB4ES38S4R
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| Record Status |
Validated (UNII)
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| Record Version |
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58320
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1-Amino-2-propanone
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DTXSID10183939
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C006495
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