U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class
Concept
Record UNII
ZAA5KE2UAS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HPN-424
Code English
PSMA/CD3 TRI-SPECIFIC T-CELL ACTIVATING CONSTRUCT HPN424
Common Name English
HPN424
Code English
HPN 424 [WHO-DD]
Common Name English
Code System Code Type Description
FDA UNII
ZAA5KE2UAS
Created by admin on Sat Dec 16 14:23:49 UTC 2023 , Edited by admin on Sat Dec 16 14:23:49 UTC 2023
PRIMARY
NCI_THESAURUS
C156681
Created by admin on Sat Dec 16 14:23:49 UTC 2023 , Edited by admin on Sat Dec 16 14:23:49 UTC 2023
PRIMARY
This is a non-substance concept
Related Record Type Details
TARGET->LIGAND
TARGET->LIGAND
The albumin binding domain of HPN424 enables the molecule to be recycled by FcRn-mediated mechanisms, thereby increasing the serum half-life of the molecule and prolonging its pharmacological effects.
TARGET -> ACTIVATOR
Related Record Type Details
ACTIVE MOIETY
This is a non-substance concept