MECARBINATE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H15NO3
Molecular Weight	233.2631
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MECARBINATE

Structure Search

SMILES

CCOC(=O)C1=C(C)N(C)C2=C1C=C(O)C=C2

InChI

InChIKey=YTBNTDMBGXAOCG-UHFFFAOYSA-N

InChI=1S/C13H15NO3/c1-4-17-13(16)12-8(2)14(3)11-6-5-9(15)7-10(11)12/h5-7,15H,4H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C13H15NO3
Molecular Weight	233.2631
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.selleckchem.com/datasheet/mecarbinate-Datasheet.html | https://www.ncbi.nlm.nih.gov/pubmed/5604597

Mecarbinate is a chemical intermediate of arbidol hydrochloride. Dimecarbin is used in the treatment of hypertension in Russia.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Hypertension 567 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5604597 https://www.ncbi.nlm.nih.gov/pubmed/5621782	Primary		Approved 8429	Dimecarbinum Approved Use Hypertension

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Treatment of hypertension: 0,01–0,02 g 3–4 times a day during 20-30 days

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:20:46 GMT 2023` Edited by `admin` on `Sat Dec 16 17:20:46 GMT 2023`
Record UNII	Z927X3UJ2W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MECARBINATE

Official Name

English

ETHYL 5-HYDROXY-1,2-DIMETHYLINDOLE-3-CARBOXYLATE

Systematic Name

English

mecarbinate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

Code System Code Type Description

CAS

15574-49-9

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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FDA UNII

Z927X3UJ2W

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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NCI_THESAURUS

C66065

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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EVMPD

SUB08671MIG

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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MESH

C001010

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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INN

2432

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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ChEMBL

CHEMBL1881106

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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PUBCHEM

616236

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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EPA CompTox

DTXSID9046289

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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SMS_ID

100000081774

Created by admin on Sat Dec 16 17:20:46 GMT 2023 , Edited by admin on Sat Dec 16 17:20:46 GMT 2023

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