Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H9ClF8N2O4 |
| Molecular Weight | 492.705 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC(OC(F)(F)F)C(F)(F)OC1=C(Cl)C=C(NC(=O)NC(=O)C2=C(F)C=CC=C2F)C=C1
InChI
InChIKey=NJPPVKZQTLUDBO-UHFFFAOYSA-N
InChI=1S/C17H9ClF8N2O4/c18-8-6-7(4-5-11(8)31-16(22,23)14(21)32-17(24,25)26)27-15(30)28-13(29)12-9(19)2-1-3-10(12)20/h1-6,14H,(H2,27,28,29,30)
| Molecular Formula | C17H9ClF8N2O4 |
| Molecular Weight | 492.705 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Novaluron is an insecticide of the benzoylphenyl
urea class that inhibits chitin synthesis, affecting the moulting stages of insect development. It
acts by ingestion and contact, and causes abnormal endocuticular deposition and abortive
moulting. Novaluron has been registered as an insecticide for food crops and ornamentals in a number
of countries. WHO has assessed novaluron for use as a mosquito larvicide in drinking-water
in containers, particularly to control dengue fever. The recommended dosage of novaluron in
potable water in containers should not exceed 0.05 mg/litre under the WHO Pesticides
Evaluation Scheme.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Biorational agents--mechanism and importance in IPM and IRM programs for controlling agricultural pests. | 2001 |
|
| Novaluron (Rimon), a novel IGR--mechanism, selectivity and importance in IPM programs. | 2002 |
|
| Laboratory and field evaluation of novaluron, a new acylurea insect growth regulator, against Aedes aegypti (Diptera: Culicidae). | 2003 Dec |
|
| Laboratory and field evaluations of novaluron, a new insect growth regulator (IGR), against Culex mosquitoes. | 2003 Dec |
|
| Novaluron (Rimon), a novel IGR: potency and cross-resistance. | 2003 Dec |
|
| Comparison of the efficacy and safety of moclobemide and imipramine in the treatment of depression in Indian patients. | 2005 Apr |
|
| Biorational insecticides: mechanism and cross-resistance. | 2005 Apr |
|
| Acute and sublethal toxicity of novaluron, a novel chitin synthesis inhibitor, to Leptinotarsa decemlineata (Coleoptera: Chrysomelidae). | 2005 Nov |
|
| Resistance potential of colorado potato beetle (Coleoptera: Chrysomelidae) to novaluron. | 2005 Oct |
|
| Hazards and uptake of chitin synthesis inhibitors in bumblebees Bombus terrestris. | 2006 Aug |
|
| Effect of Novaluron (Rimon 10 EC) on the mosquitoes Anopheles albimanus, Anopheles pseudopunctipennis, Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Chiapas, Mexico. | 2006 Dec |
|
| Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts. | 2006 Jan |
|
| Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata. | 2007 |
|
| Novel life stage targets against plum curculio, Conotrachelus nenuphar (Herbst), in apple integrated pest management. | 2007 Aug |
|
| Method of fast trace microanalysis of the chiral pesticides epoxiconazole and novaluron in soil samples using off-line flow-through extraction and on-column direct large volume injection in reversed-phase high performance liquid chromatography. | 2007 Dec |
|
| Topical, residual and ovicidal contact toxicity of three reduced-risk insecticides against the European corn borer, Ostrinia nubilalis (Lepidoptera: Crambidae), on potato. | 2007 Dec |
|
| Evaluation of novaluron as a feed-through insecticide for control of immature sand flies (Diptera: Psychodidae). | 2007 Jul |
|
| Synergism between cis-permethrin and benzoyl phenyl urea insect growth regulators against Aedes aegypti larvae. | 2007 Mar |
|
| Field evaluation of novaluron, a chitin synthesis inhibitor larvicide, against mosquito larvae in polluted water in urban areas of Bangkok, Thailand. | 2007 May |
|
| Reduced viability of Colorado potato beetle, Leptinotarsa decemlineata, eggs exposed to novaluron. | 2008 Jan |
|
| Survey of insect growth regulator (IGR) resistance in house flies (Musca domestica L.) from southwestern Turkey. | 2009 Dec |
|
| Stimulatory and suppressive effects of novaluron on the Colorado potato beetle reproduction. | 2009 Dec |
|
| Fifty years of the integrated control concept: moving the model and implementation forward in Arizona. | 2009 Dec |
|
| Impact of currently used or potentially useful insecticides for canola agroecosystems on Bombus impatiens (Hymenoptera: Apidae), Megachile rotundata (Hymentoptera: Megachilidae), and Osmia lignaria (Hymenoptera: Megachilidae). | 2009 Feb |
|
| Analysis of errors in the structure determination of MsbA. | 2009 Feb |
|
| Flexibility and dynamics of NhaA Na+/H+-antiporter of Escherichia coli studied by Fourier transform infrared spectroscopy. | 2009 Feb |
|
| Dopamine and inhibitory action control: evidence from spontaneous eye blink rates. | 2009 Jul |
|
| Neuroimaging in anxiety disorders. | 2009 Jun |
|
| Reduced egg viability in codling moth Cydia pomonella (L.) (Lepidoptera: Tortricidae) following adult exposure to novaluron. | 2009 Mar |
|
| Curative activity of insecticides against plum curculio (Coleoptera: Curculionidae) in tart cherries. | 2009 Oct |
|
| Efficacy of novaluron against Culex quinquefasciatus in small- and medium-scale trials, India. | 2009 Sep |
|
| The dominant Anopheles vectors of human malaria in the Americas: occurrence data, distribution maps and bionomic précis. | 2010 Aug 16 |
|
| Etoricoxibium picrate. | 2010 Dec 11 |
|
| Impact of five commercial baits containing chitin synthesis inhibitors on the protist community in Reticulitermes flavipes (Isoptera: Rhinotermitidae). | 2010 Feb |
|
| Bioefficacy of insecticides against Leucinodes orbonalis on brinjal. | 2010 Jul |
|
| Developmental disruptions induced by insect growth regulator (Novaluron) in Bufo melanostictus tadpoles. | 2010 Jul |
|
| Laboratory evaluation of novaluron as a rodent feed-through insecticide against sand fly larvae (Diptera: Psychodidae). | 2010 Mar |
|
| Synthesis and insecticidal activity of heptafluoroisopropyl-containing benzoylphenylurea structures. | 2010 Mar 10 |
|
| Activity of broad-spectrum and reduced-risk insecticides on various life stages of cranberry fruitworm (Lepidoptera: Pyralidae) in highbush blueberry. | 2010 Oct |
|
| Acute human lethal toxicity of agricultural pesticides: a prospective cohort study. | 2010 Oct 26 |
|
| Field evaluation of pyriproxyfen and spinosad mixture for the control of insecticide resistant Aedes aegypti in Martinique (French West Indies). | 2010 Sep 16 |
Patents
Sample Use Guides
In a test for acute oral toxicity, five male and five female mice (strain Hsd/Ola:ICR) were
given novaluron (purity, 99.3%) at a limit dose of 5000 mg/kg bw (20 ml/kg) by gavage in
distilled water. There were no mortalities or clinical signs of toxicity.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
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| Record UNII |
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EPA PESTICIDE CODE |
124002
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novaluron
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m8079
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Novaluron
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