BEPIROVIRSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid
Nucleic Acid Type	RNAI
Sequence Origin	VIRAL
Sequence Type	OLIGONUCLEOTIDE
Record UNII	Z87O6SM01N
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

IONIS HBVRX

Preferred Name

English

BEPIROVIRSEN

Official Name

English

ISIS-505358

Code

English

DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-G-G-T-G-A-A-G-M5C-G-A-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O

Common Name

English

GSK-3228836B

Code

English

Showing 1 to 5 of 13 entries

Previous1 2 3Next

Show entries

Code System

Code

Type

Description

INN

11450

PRIMARY

USAN

JK-163

PRIMARY

SMS_ID

300000018718

PRIMARY

FDA UNII

Z87O6SM01N

PRIMARY

NCI_THESAURUS

C175748

PRIMARY

Showing 1 to 5 of 6 entries

Previous1 2Next

Subunit 0

Show entries

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Showing 1 to 2 of 2 entries

Show entries

Linkage	Site Range	Site Count
Phosporothioate	1_1-1_19	19 / 19

Showing 1 to 1 of 1 entries

Show entries

Related Record

Type

Details


					77H9EM77P7

HEPATITIS B VIRUS

TARGET ORGANISM->INHIBITOR

Amount:

Showing 1 to 1 of 1 entries

Show entries

Related Record

Type

Details


					Z87O6SM01N

ACTIVE MOIETY

Amount:

Showing 1 to 1 of 1 entries

Structural Modifications

Show entries

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOSIDE BASE SUBSTITUTION	[1_2] [1_13] [1_20]	SITE_SPECIFIC	1_2; 1_13; 1_20		5-METHYLCYTOSINE	6R795CQT4H

Showing 1 to 1 of 1 entries

Show entries

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	NUMBER

Showing 1 to 1 of 1 entries