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Details

Stereochemistry ACHIRAL
Molecular Formula CO3.Ca.Cl.2K.Mg.3HO
Molecular Weight 289.0636
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of CALCIUM MAGNESIUM POTASSIUM CARBONATE CHLORIDE HYDROXIDE

SMILES

C(=O)([O-])[O-].[Ca+2].[Cl-].[K+2].[K+2].[Mg+2].[OH-].[OH-].[OH-]

InChI

InChIKey=RUGQTQJQCSDUFS-UHFFFAOYSA-H
InChI=1S/CH2O3.Ca.ClH.2K.Mg.3H2O/c2-1(3)4;;;;;;;;/h(H2,2,3,4);;1H;;;;3*1H2/q;+2;;3*+2;;;/p-6

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.4609
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula CO3
Molecular Weight 60.009
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Mg
Molecular Weight 24.3051
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula K
Molecular Weight 39.0983
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

VASCULERA (diosmiplex) consists of diosmin glycoside in combination with alkaline granules, alka4-complex. Alka4-complex contains 30 mg of a proprietary, structured, highly alkaline agglomeration of reactive magnesium hydroxide (Mg(OH)2, molecular weight 58.3), potassium chloride (KCl, molecular weight 74.6) and potassium hydroxide (KOH, molecular weight 56.1) held apart from each other in a matrix of calcium carbonate (CaCO3, molecular weight 100.1), microcrystalline cellulose and croscarmellose sodium. VASCULERA is indicated for the clinical dietary management of the metabolic processes associated with chronic venous insufficiency (CVI). VASCULERA acts by restoring toward normal the metabolic aspects of CVI including modulation of venous tone and capillary resistance, management of lymphatic drainage, and inflammation in the microcirculation. Alka4-complex has been shown in preclinical and clinical studies to act as an acid buffering agent in the gut and to counteract the effects of increased acid production systemically. Clinical studies have shown that alka4-complex in VASCULERA can reduce acidosis under extreme exercise loads. The specially agglomerated matrix of alka4-complex has been shown to resist neutralization by acid solutions. In addition, the alka4-complex has been shown to reduce the acid producing effects of certain foods by buffering the acidity in the gastrointestinal tract, while allowing a sufficient portion of the complex to survive in the stomach, and is absorbed in the small intestine thereby being available to manage mild acidosis.

Approval Year

Conditions

Conditions

Sample Use Guides

VASCULERA can be taken with or without food.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 03:49:57 UTC 2021
Edited
by admin
on Sat Jun 26 03:49:57 UTC 2021
Record UNII
Z7R65IFU98
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM MAGNESIUM POTASSIUM CARBONATE CHLORIDE HYDROXIDE
WHO-DD  
Systematic Name English
ALKA4-COMPLEX
Common Name English
ALKA 4-COMPLEX [WHO-DD]
Common Name English
Code System Code Type Description
DRUG BANK
DB14497
Created by admin on Sat Jun 26 03:49:57 UTC 2021 , Edited by admin on Sat Jun 26 03:49:57 UTC 2021
PRIMARY
FDA UNII
Z7R65IFU98
Created by admin on Sat Jun 26 03:49:57 UTC 2021 , Edited by admin on Sat Jun 26 03:49:57 UTC 2021
PRIMARY
CAS
1224727-39-2
Created by admin on Sat Jun 26 03:49:57 UTC 2021 , Edited by admin on Sat Jun 26 03:49:57 UTC 2021
PRIMARY