Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H8N4O3 |
| Molecular Weight | 196.1634 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)NC2=C1C(=O)N(C)C(=O)N2
InChI
InChIKey=NOFNCLGCUJJPKU-UHFFFAOYSA-N
InChI=1S/C7H8N4O3/c1-10-3-4(8-6(10)13)9-7(14)11(2)5(3)12/h1-2H3,(H,8,13)(H,9,14)
| Molecular Formula | C7H8N4O3 |
| Molecular Weight | 196.1634 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin. | 2001 Aug 15 |
|
| CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. | 2002 Apr |
|
| A population phenotyping study of three drug-metabolizing enzymes in Kyushu, Japan, with use of the caffeine test. | 2002 Aug |
|
| Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction. | 2002 Aug |
|
| Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer. | 2002 Dec 27 |
|
| Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug. | 2003 Feb |
|
| Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study. | 2004 |
|
| Catabolism of caffeine in plants and microorganisms. | 2004 May 1 |
|
| Measurement of caffeine and five of the major metabolites in urine by high-performance liquid chromatography/tandem mass spectrometry. | 2005 Mar |
|
| Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. | 2006 Dec |
|
| Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay. | 2007 Feb |
|
| CYP2A6 activity in a healthy Spanish population: effect of age, sex, smoking, and oral contraceptives. | 2008 May |
|
| Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers. | 2009 Aug |
|
| Plant polyphenol curcumin significantly affects CYP1A2 and CYP2A6 activity in healthy, male Chinese volunteers. | 2010 Jun |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:14:47 UTC 2023
by
admin
on
Fri Dec 15 19:14:47 UTC 2023
|
| Record UNII |
Z633Z7KAJU
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Z633Z7KAJU
Created by
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DTXSID30187499
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251-706-2
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91611
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33868-03-0
Created by
admin on Fri Dec 15 19:14:47 UTC 2023 , Edited by admin on Fri Dec 15 19:14:47 UTC 2023
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