Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC(Cl)=C(C(Cl)=C1)C2=C(Cl)C=CC=C2Cl
InChI
InChIKey=MTCPZNVSDFCBBE-UHFFFAOYSA-N
InChI=1S/C12H5Cl5/c13-6-4-9(16)12(10(17)5-6)11-7(14)2-1-3-8(11)15/h1-5H
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 2,2',4,6,6'-pentachlorobiphenyl induces apoptosis in human monocytic cells. | 2000 Nov 15 |
|
| 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. | 2003 May 15 |
|
| c-Src is the primary signaling mediator of polychlorinated biphenyl-induced interleukin-8 expression in a human microvascular endothelial cell line. | 2006 Jul |
|
| Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells. | 2006 Jun |
|
| Co-planar 3,3',4,4',5-pentachlorinated biphenyl and non-co-planar 2,2',4,6,6'-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor alpha to aryl hydrocarbon receptor target genes. | 2007 Sep 1 |
|
| PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase. | 2009 Oct 15 |
|
| Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression. | 2010 Jul |
|
| In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. | 2011 May |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 03:10:20 GMT 2023
by
admin
on
Sat Dec 16 03:10:20 GMT 2023
|
| Record UNII |
Z4YYF101N3
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| Record Status |
Validated (UNII)
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| Record Version |
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admin on Sat Dec 16 03:10:20 GMT 2023 , Edited by admin on Sat Dec 16 03:10:20 GMT 2023
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