Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H26ClN3O.H2O4S |
| Molecular Weight | 433.95 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OS(O)(=O)=O.CCN(CCO)CCC[C@@H](C)NC1=C2C=CC(Cl)=CC2=NC=C1
InChI
InChIKey=JCBIVZZPXRZKTI-PFEQFJNWSA-N
InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)/t14-;/m1./s1
| Molecular Formula | H2O4S |
| Molecular Weight | 98.078 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C18H26ClN3O |
| Molecular Weight | 335.872 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign). | 2010-10-21 |
|
| Ileocecal intussusception in the adult population: case series of two patients. | 2010-05 |
|
| [The ERG contribution in early diagnosis of chloroquine and hydroxychloroquine maculopathy]. | 2010-04 |
|
| Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature. | 2010-03-23 |
|
| [Chilblain lupus in an adolescent]. | 2010-03-06 |
|
| Vimentin compartmentalization in discoid lupus. | 2010-02 |
|
| Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy. | 2009-08-20 |
|
| Autoimmune retinopathy in systemic lupus erythematosus: histopathologic features. | 2009-04-28 |
|
| Using multifocal ERG ring ratios to detect and follow Plaquenil retinal toxicity: a review : Review of mfERG ring ratios in Plaquenil toxicity. | 2009-02 |
|
| Long-Term Alendronate Use Not without Consequences? | 2009 |
|
| [Combined basic therapy of rheumatoid arthritis with methotrexate and plaquenil]. | 2009 |
|
| Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases. | 2009 |
|
| Retinal toxicity secondary to Plaquenil therapy. | 2008-02 |
|
| Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). | 2008 |
|
| Shared decision-making based on different features of risk in the context of diabetes mellitus and rheumatoid arthritis. | 2007-12 |
|
| Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma. | 2005-05 |
|
| [Intolerance to hydroxychloroquine marketed in Spain (Dolquine) in patients with autoimmune conditions]. | 2004-11 |
|
| Assessing hydroxychloroquine toxicity by the multifocal ERG. | 2004-01 |
|
| Methimazole-induced lupus erythematosus: a case report. | 2003-12 |
|
| Electrochemical study of hydroxychloroquine and its determination in plaquenil by differential pulse voltammetry. | 2003-06-01 |
|
| Frequency of adverse drug reactions in patients with systemic lupus erythematosus. | 2003-03 |
|
| Methotrexate-induced optic neuropathy. | 2002-12 |
|
| Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis. | 2001 |
|
| Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine. | 1996-11-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 19:47:44 GMT 2025
by
admin
on
Wed Apr 02 19:47:44 GMT 2025
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| Record UNII |
Z4W6RXH4ZD
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Preferred Name | English | ||
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2488706-20-1
Created by
admin on Wed Apr 02 19:47:44 GMT 2025 , Edited by admin on Wed Apr 02 19:47:44 GMT 2025
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Z4W6RXH4ZD
Created by
admin on Wed Apr 02 19:47:44 GMT 2025 , Edited by admin on Wed Apr 02 19:47:44 GMT 2025
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73416236
Created by
admin on Wed Apr 02 19:47:44 GMT 2025 , Edited by admin on Wed Apr 02 19:47:44 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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RACEMATE -> ENANTIOMER |
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PARENT -> SALT/SOLVATE |
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