BGC-20-1531 free base

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H24N2O6S
Molecular Weight	492.544
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(N=C1)C2=CC=C(OCC3=C(C)OC(=C3)C(=O)NS(=O)(=O)C4=CC=CC=C4C)C=C2

InChI

InChIKey=IXDVRRPNWPOPGV-UHFFFAOYSA-N

InChI=1S/C26H24N2O6S/c1-17-6-4-5-7-25(17)35(30,31)28-26(29)24-14-20(18(2)34-24)16-33-21-10-8-19(9-11-21)23-13-12-22(32-3)15-27-23/h4-15H,16H2,1-3H3,(H,28,29)

HIDE SMILES / InChI

Molecular Formula	C26H24N2O6S
Molecular Weight	492.544
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Prostanoid EP4 receptor 12 Target ID: CHEMBL1836 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24703233	Antagonist 2849		3.0 nM [Ki]
Prostaglandin E2 receptor EP4 subtype 3 Target ID: P35408 Gene ID: 5734.0 Gene Symbol: PTGER4 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/21681585	Antagonist 2849

PubMed

Title	Date	PubMed
The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the prostaglandin E2 human model of headache.	2011-10	21681585
BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache.	2009-01	19154437

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:46:28 GMT 2025` Edited by `admin` on `Wed Apr 02 05:46:28 GMT 2025`
Record UNII	Z49JYU6T3P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-Furancarboxamide, 4-[[4-(5-methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-

Preferred Name

English

BGC-20-1531 free base

Common Name

English

N-[[4-[[4-(5-Methoxypyridin-2-yl)phenoxy]methyl]-5-methylfuran-2-yl]carbonyl]-2-methylbenzenesulfonamide

Systematic Name

English

4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide

Systematic Name

English

4-((4-(5-Methoxypyridin-2-yl)phenoxy)methyl)-5-methyl-n-(2-methylphenyl)sulfonyl-furan-2-carboximidic acid

Systematic Name

English

Code System Code Type Description

PUBCHEM

18444613

Created by admin on Wed Apr 02 05:46:28 GMT 2025 , Edited by admin on Wed Apr 02 05:46:28 GMT 2025

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FDA UNII

Z49JYU6T3P

Created by admin on Wed Apr 02 05:46:28 GMT 2025 , Edited by admin on Wed Apr 02 05:46:28 GMT 2025

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EPA CompTox

DTXSID001351969

Created by admin on Wed Apr 02 05:46:28 GMT 2025 , Edited by admin on Wed Apr 02 05:46:28 GMT 2025

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CAS

736183-35-0

Created by admin on Wed Apr 02 05:46:28 GMT 2025 , Edited by admin on Wed Apr 02 05:46:28 GMT 2025

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BGC-20-1531

SALT/SOLVATE -> PARENT

Amount: