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Details

Stereochemistry RACEMIC
Molecular Formula C9H14N2O.2ClH
Molecular Weight 239.142
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FENOXYPROPAZINE DIHYDROCHLORIDE

SMILES

Cl.Cl.CC(COC1=CC=CC=C1)NN

InChI

InChIKey=ICESXWSYSZBABF-UHFFFAOYSA-N
InChI=1S/C9H14N2O.2ClH/c1-8(11-10)7-12-9-5-3-2-4-6-9;;/h2-6,8,11H,7,10H2,1H3;2*1H

HIDE SMILES / InChI
Molecular Formula C9H14N2O
Molecular Weight 166.2203
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phenoxypropazine is a monoamine oxidase inhibitor. It was used in the treatment of depression. Phenoxypropazine was introduced in 1961 and withdrawn after 5 years on the market due to dose- and time-unrelated liver damage not identified in animal experiments.

CNS Activity

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
 0.01 mM [Ki]
PubMed

PubMed

TitleDatePubMed
A preliminary study of phenoxypropazine in the treatment of depression.
1963 Apr
Preliminary report on phenoxypropazine.
1963 May
A COMPARISON OF PHENOXYPROPAZINE AND AMYTRYPTILINE IN DEPRESSION.
1963 Oct

Sample Use Guides

Substance Class Chemical
Created
by admin
on Sat Dec 16 19:04:38 UTC 2023
Edited
by admin
on Sat Dec 16 19:04:38 UTC 2023
Record UNII
Z3R5MM953N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FENOXYPROPAZINE DIHYDROCHLORIDE
Common Name English
HYDRAZINE, (1-METHYL-2-PHENOXYETHYL)-, HYDROCHLORIDE (1:2)
Systematic Name English
Code System Code Type Description
PUBCHEM
69923706
Created by admin on Sat Dec 16 19:04:39 UTC 2023 , Edited by admin on Sat Dec 16 19:04:39 UTC 2023
PRIMARY
FDA UNII
Z3R5MM953N
Created by admin on Sat Dec 16 19:04:39 UTC 2023 , Edited by admin on Sat Dec 16 19:04:39 UTC 2023
PRIMARY
CAS
1803608-13-0
Created by admin on Sat Dec 16 19:04:39 UTC 2023 , Edited by admin on Sat Dec 16 19:04:39 UTC 2023
PRIMARY
Related Record Type Details
Structure of FENOXYPROPAZINE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FENOXYPROPAZINE
ACTIVE MOIETY
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