Details
Stereochemistry | ACHIRAL |
Molecular Formula | C22H39NO3 |
Molecular Weight | 365.55 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 2 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCCC(O)=O
InChI
InChIKey=YGFYZZQGVSUXJE-HZJYTTRNSA-N
InChI=1S/C22H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)23-20-17-19-22(25)26/h6-7,9-10H,2-5,8,11-20H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-
Molecular Formula | C22H39NO3 |
Molecular Weight | 365.55 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 2 |
Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/2735495
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2735495
N-Linoleoyl-4-aminobutyric acid (also known as GABA-linoleamide) is a GABA-ergic compound, which can lead to the development of oral dyskinesia, when in use in combination with haloperidol.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
[Psychopharmacologic profile of a new product: GABA linoleamide (Gabalid)]. | 1982 Oct |
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[Action of GABA-linoleamide on blood cholesterol in rats]. | 1983 Jan |
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[2 new GABA-ergics (GABA-linoleamide and GABA-steatamide). On 2 experimental models of depression]. | 1985 Jun |
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[Effect of GABA-linoleamide and glycine linoleamide on pentamethylenetetrazole convulsions]. | 1986 Jul-Sep |
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[Vacuous chewing after haloperidol and GABA-linoleamide administration in the rat]. | 1986 Nov |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2735495
Oral dyskinesia in rats: Wistar male rats received haloperidol (0.6 mg.kg-1, i.p.) and GABA-linoleamide (10 mg.kg-1, i.p.) and have been observed 120 or 240 minutes after administrations, during 2 minutes, in order to quantify oral dyskinesias (vacuous chewing movements, teeth chattering & grating) and catalepsy.
Route of Administration:
Intraperitoneal
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:49:29 GMT 2023
by
admin
on
Sat Dec 16 08:49:29 GMT 2023
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Record UNII |
Z3NMX9471T
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Record Status |
Validated (UNII)
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Record Version |
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84393-31-7
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DTXSID801182685
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Z3NMX9471T
Created by
admin on Sat Dec 16 08:49:29 GMT 2023 , Edited by admin on Sat Dec 16 08:49:29 GMT 2023
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