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Details

Stereochemistry ACHIRAL
Molecular Formula 3Cl.Cr
Molecular Weight 158.355
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHROMIC CHLORIDE ANHYDROUS

SMILES

[Cl-].[Cl-].[Cl-].[Cr+3]

InChI

InChIKey=QSWDMMVNRMROPK-UHFFFAOYSA-K
InChI=1S/3ClH.Cr/h3*1H;/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula Cr
Molecular Weight 51.9961
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Chromium sulfate(III) hexahydrate or chromium sulphate, a trivalent compound of chromium that was investigated as a toxic compound. Experiments on rodent have shown chromium sulfate produced severe and widespread effects in the nasal cavity, larynx, lungs, and mediastinal lymph node. Effects were characterized by the accumulation of foreign material, infiltration of alveolar macrophages, septal cell hyperplasia, and granulomatous and chronic inflammation. Besides, chromium sulphate exerted a disadvantageous effect on the skeleton, as it decreases bone density and resistance.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
CHROMIUM

Approved Use

Chromium 4 mcg/mL (Chromic Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition. Administration helps to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Launch Date

1.12000316E12
PubMed

PubMed

TitleDatePubMed
Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin.
1994 Jun
Silicate antibodies in women with silicone breast implants: development of an assay for detection of humoral immunity.
1996 Mar
Activation of MAPKs in human bronchial epithelial cells exposed to metals.
1998 Sep
Thirteen-week subchronic rat inhalation toxicity study with a recovery phase of trivalent chromium compounds, chromic oxide, and basic chromium sulfate.
1999 Dec
Status of antioxidant defense system in chromium-induced Swiss mice tissues.
2004 Jul
Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium.
2007 Aug
Effects of subchronic exposure via drinking water to a mixture of eight water-contaminating metals: a biochemical and histopathological study in male rats.
2007 Nov
Immunosuppressive effect of subchronic exposure to a mixture of eight heavy metals, found as groundwater contaminants in different areas of India, through drinking water in male rats.
2007 Oct
The peripheral quantitative computed tomographic and densitometric analysis of skeletal tissue in male Wistar rats after chromium sulfate treatment.
2017 Sep 21
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:32:21 UTC 2023
Edited
by admin
on Fri Dec 15 16:32:21 UTC 2023
Record UNII
Z310X5O5RP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHROMIC CHLORIDE ANHYDROUS
HSDB  
Common Name English
CHROMIUM CHLORIDE (CRCL3)
Common Name English
CHROMIUM TRICHLORIDE
Systematic Name English
CHROMIUM (III) CHLORIDE
Common Name English
CHROMIC CHLORIDE [MI]
Common Name English
Chromic chloride [WHO-DD]
Common Name English
CHROMIUM(III) CHLORIDE, ANHYDROUS
Common Name English
CHROMIC CHLORIDE ANHYDROUS [HSDB]
Common Name English
CHROMIUM(III) CHLORIDE
Systematic Name English
CHROMIUM(3+) CHLORIDE
Systematic Name English
TRICHLOROCHROMIUM
Systematic Name English
Code System Code Type Description
SMS_ID
100000091783
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
WIKIPEDIA
CHROMIUM(III) CHLORIDE
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
ECHA (EC/EINECS)
233-038-3
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
EVMPD
SUB127348
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID20858722
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
HSDB
6341
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
CAS
10025-73-7
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
DRUG BANK
DB09129
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
CHEBI
53351
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
FDA UNII
Z310X5O5RP
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
PUBCHEM
24808
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY
MERCK INDEX
m3496
Created by admin on Fri Dec 15 16:32:21 UTC 2023 , Edited by admin on Fri Dec 15 16:32:21 UTC 2023
PRIMARY Merck Index
Related Record Type Details
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY