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Details

Stereochemistry ACHIRAL
Molecular Formula C12H5Br5O
Molecular Weight 564.688
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,3,4,5,6-PENTABROMODIPHENYL ETHER

SMILES

BrC1=C(Br)C(Br)=C(OC2=CC=CC=C2)C(Br)=C1Br

InChI

InChIKey=ACRQLFSHISNWRY-UHFFFAOYSA-N
InChI=1S/C12H5Br5O/c13-7-8(14)10(16)12(11(17)9(7)15)18-6-4-2-1-3-5-6/h1-5H

HIDE SMILES / InChI

Molecular Formula C12H5Br5O
Molecular Weight 564.688
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Absorption, disposition and excretion of polybrominated diphenyl ethers (PBDEs) in chicken.
2007-01
PBDEs and PBBs in the adipose tissue of women from Spain.
2007-01
Continental scale passive air sampling of persistent organic pollutants using rapidly equilibrating thin films (POGs).
2006-11
Neurotoxicity of the pentabrominated diphenyl ether mixture, DE-71, and hexabromocyclododecane (HBCD) in rat cerebellar granule cells in vitro.
2006-11
Within- and among-clutch variation of organohalogenated contaminants in eggs of great tits (Parus major).
2006-11
Interfollicular fibrosis in the thyroid of the harbour porpoise: an endocrine disruption?
2006-11
Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development.
2006-09-01
A multilevel approach to predict toxicity in copepod populations: assessment of growth, genetics, and population structure.
2006-08-12
An intercalibration study on organobromine compounds: Results on polybrominated diphenylethers and related dioxin-like compounds.
2006-06
Inhibition of metamorphosis in tadpoles of Xenopus laevis exposed to polybrominated diphenyl ethers (PBDEs).
2006-06
Effects of deBDE and PCB-126 on hepatic concentrations of PBDEs and methoxy-PBDEs in Atlantic tomcod.
2006-05-15
Organohalogen contaminants and metabolites in beluga whale (Delphinapterus leucas) liver from two Canadian populations.
2006-05
Organohalogen chemicals in human blood from the United Kingdom.
2006-05
Biotransformation of polybrominated diphenyl ethers and polychlorinated biphenyls in beluga whale (Delphinapterus leucas) and rat mammalian model using an in vitro hepatic microsomal assay.
2006-04-20
Gene expression and estrogen sensitivity in rat uterus after developmental exposure to the polybrominated diphenylether PBDE 99 and PCB.
2006-03-15
Proteomic evaluation of neonatal exposure to 2,2 ,4,4 ,5-pentabromodiphenyl ether.
2006-02
Effects of developmental exposure to 2,2 ,4,4 ,5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in rats.
2006-02
Developmental and behavioral effects of embryonic exposure to the polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus).
2006-02
Tissue disposition, excretion and metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) in male Sprague-Dawley rats.
2006-01
Accumulation, metabolism, and food-chain transfer of chlorinated and brominated contaminants in subadult white whales (Delphinapterus leucas) and narwhals (Monodon monoceros) from Svalbard, Norway.
2006-01
Tissue localisation of tetra- and pentabromodiphenyl ether congeners (BDE-47, -85 and -99) in perinatal and adult C57BL mice.
2006-01
Absorption of [14C]-tetrabromodiphenyl ether (TeBDE) through human and rat skin in vitro.
2006
New multiresidue analytical method dedicated to trace level measurement of brominated flame retardants in human biological matrices.
2005-12-30
Concentrations of polybrominated diphenyl ethers, polychlonnated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later.
2005-12-15
Body burdens of polybrominated diphenyl ethers among urban anglers.
2005-12
Exposure to polybrominated diphenyl ethers (PBDEs): changes in thyroid, vitamin A, glutathione homeostasis, and oxidative stress in American kestrels (Falco sparverius).
2005-12
Identification, quantification, and synthesis of a novel dimethoxylated polybrominated biphenyl in marine mammals caught off the coast of Japan.
2005-11-15
Passive air sampling of polychlorinated biphenyls, organochlorine compounds, and polybrominated diphenyl ethers across Asia.
2005-11-15
Multivariate data analyses of chlorinated and brominated contaminants and biological characteristics in adult guillemot (Uria aalge) from the Baltic Sea.
2005-11-15
Brief postnatal PBDE exposure alters learning and the cholinergic modulation of attention in rats.
2005-11
Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components.
2005-11
Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships.
2005-11
Studies examine whether persistent organic agents may be responsible for rise in lymphoma rates.
2005-10-19
Polybrominated diphenyl ethers in indoor dust in Ottawa, Canada: implications for sources and exposure.
2005-09-15
Dietary accumulation efficiencies and biotransformation of polybrominated diphenyl ethers in farmed Atlantic salmon (Salmo salar).
2005-09
A commercial mixture of the brominated flame retardant pentabrominated diphenyl ether (DE-71) induces respiratory burst in human neutrophil granulocytes in vitro.
2005-09
In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture.
2005-08-22
Probing new approaches using atmospheric pressure photo ionization for the analysis of brominated flame retardants and their related degradation products by liquid chromatography-mass spectrometry.
2005-07-29
A retrospective study of PBDEs and PCBs in human milk from the Faroe Islands.
2005-07-14
Ultrastructural changes observed in rat ovaries following in utero and lactational exposure to low doses of a polybrominated flame retardant.
2005-07-04
Effects of selected polybrominated diphenyl ether flame retardants on lake trout (Salvelinus namaycush).
2005-06
Organohalogen levels in harbor seal (Phoca vitulina) pups increase with duration of nursing.
2005-05-14
Time trends of atmospheric PBDEs inferred from archived U.K. herbage.
2005-04-15
Modern and historical fluxes of halogenated organic contaminants to a lake in the Canadian arctic, as determined from annually laminated sediment cores.
2005-04-15
Effects of pentabrominated diphenyl ether (PBDE-99) on vitamin status in domestic duck (Anas platyrhynchos) hatchlings.
2005-04-09
Polybrominated diphenyl ethers (PBDEs) in U.S. computers and domestic carpet vacuuming: possible sources of human exposure.
2005-04-09
Rapid identification of RoHS-relevant flame retardants from polymer housings by ultrasonic extraction and RP-HPLC/UV.
2005-02-25
Polybrominated diphenyl ethers in house dust and clothes dryer lint.
2005-02-15
Developmental exposure to low dose PBDE 99: effects on male fertility and neurobehavior in rat offspring.
2005-02
Polybrominated diphenyl ethers (PBDEs): new pollutants-old diseases.
2003-10
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:33:01 GMT 2025
Edited
by admin
on Mon Mar 31 20:33:01 GMT 2025
Record UNII
Z2L01G821E
Record Status Validated (UNII)
Record Version
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Name Type Language
2,3,4,5,6-PENTABROMODIPHENYL ETHER
Common Name English
PBDE 116
Preferred Name English
BENZENE, 1,2,3,4,5-PENTABROMO-6-PHENOXY-
Systematic Name English
Code System Code Type Description
CAS
189084-65-9
Created by admin on Mon Mar 31 20:33:01 GMT 2025 , Edited by admin on Mon Mar 31 20:33:01 GMT 2025
PRIMARY
PUBCHEM
13766702
Created by admin on Mon Mar 31 20:33:01 GMT 2025 , Edited by admin on Mon Mar 31 20:33:01 GMT 2025
PRIMARY
FDA UNII
Z2L01G821E
Created by admin on Mon Mar 31 20:33:01 GMT 2025 , Edited by admin on Mon Mar 31 20:33:01 GMT 2025
PRIMARY
EPA CompTox
DTXSID80548894
Created by admin on Mon Mar 31 20:33:01 GMT 2025 , Edited by admin on Mon Mar 31 20:33:01 GMT 2025
PRIMARY