TIAMETONIUM IODIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H30N2S.2I
Molecular Weight	488.254
Optical Activity	NONE
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[I-].[I-].CC[N+](C)(C)CCSCC[N+](C)(C)CC

InChI

InChIKey=JXCZZGMKVJZBER-UHFFFAOYSA-L

InChI=1S/C12H30N2S.2HI/c1-7-13(3,4)9-11-15-12-10-14(5,6)8-2;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula	HI
Molecular Weight	127.91241
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C12H30N2S
Molecular Weight	234.445
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13443998 | https://www.ncbi.nlm.nih.gov/pubmed/14082449 | Activitas Nervosa Superior (1966), 8, (1), 60-7

Tiametonium (also known as Thiamethon) is a lanthionamine derivative with ganglionic blocking activity. In preclinical models, Thiamethon prevents nicotine-induced convulsions in mice.

Originator

Approval Year

PubMed

Title	Date	PubMed
[ASSESSMENT OF THE CLINICAL EFFECTS OF THIAMETHONE].	1963-08	14082449

Patents

Sample Use Guides

In Vivo Use Guide

50 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:59:30 GMT 2025` Edited by `admin` on `Mon Mar 31 17:59:30 GMT 2025`
Record UNII	Z0OMD60978
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIAMETONIUM IODIDE

Official Name

English

(THIODIETHYLENE)BIS(ETHYLDIMETHYLAMMONIUM IODIDE)

Preferred Name

English

tiametonium iodide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C47796