N-MONOACETYLCYSTINE

Possibly Marketed Outside US

First approved in 2019

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H14N2O5S2
Molecular Weight	282.337
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

InChIKey=ZLCOWUKVVFVVKA-WDSKDSINSA-N

InChI=1S/C8H14N2O5S2/c1-4(11)10-6(8(14)15)3-17-16-2-5(9)7(12)13/h5-6H,2-3,9H2,1H3,(H,10,11)(H,12,13)(H,14,15)/t5-,6-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C8H14N2O5S2
Molecular Weight	282.337
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7237945 | https://pubchem.ncbi.nlm.nih.gov/compound/cystine
Curator's Comment: Not to be confused with N-acetylcysteine

N-monoacetylcystine is monoacetylated derivative of L-cystine, a covalently linked dimeric nonessential aminoacid formed by the oxidation of cysteine. N-monoacetylcystine is accumulated in the plasma of uraemic patients.

Approval Year

PubMed

Title	Date	PubMed
Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking.	2005-07-06	16000629

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:56:53 GMT 2025` Edited by `admin` on `Mon Mar 31 21:56:53 GMT 2025`
Record UNII	YXO5V2CF3F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-MONOACETYLCYSTINE

Systematic Name

English

CYSTINE, N-ACETYL-, L-

Preferred Name

English

N-ACETYL-L-CYSTINE

Systematic Name

English

N-ACETYLCYSTEINE-CYSTEINE DISULFIDE

Systematic Name

English

N-ACETYLCYSTINE

Systematic Name

English

L-CYSTINE, N-ACETYL-

Systematic Name

English

Code System Code Type Description

CAS

25779-79-7