U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C10H9N3O3S
Molecular Weight 251.262
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-HYDROXYSULFADIAZINE

SMILES

OC1=CC=C(C=C1)S(=O)(=O)NC2=NC=CC=N2

InChI

InChIKey=JQSRUHVUXRYZBW-UHFFFAOYSA-N
InChI=1S/C10H9N3O3S/c14-8-2-4-9(5-3-8)17(15,16)13-10-11-6-1-7-12-10/h1-7,14H,(H,11,12,13)

HIDE SMILES / InChI

Molecular Formula C10H9N3O3S
Molecular Weight 251.262
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
In vitro effects of sulfadiazine and its metabolites alone and in combination with pyrimethamine on Toxoplasma gondii.
1995 Mar
Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism.
2005 Jul
Structural characterization of sulfadiazine metabolites using H/D exchange combined with various MS/MS experiments.
2005 Oct
A conceptual model describing the fate of sulfadiazine and its metabolites observed in manure-amended soils.
2009 Oct
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:25:57 GMT 2025
Edited
by admin
on Mon Mar 31 19:25:57 GMT 2025
Record UNII
YX560LZ60W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-HYDROXYSULFADIAZINE
Common Name English
1-PHENOL-4-SULFONAMIDE, N-2-PYRIMIDINYL-
Preferred Name English
BENZENESULFONAMIDE, 4-HYDROXY-N-2-PYRIMIDINYL-
Systematic Name English
2-BENZENESULFONAMIDO-4-HYDROXYPYRIMIDINE
Systematic Name English
BENZENESULFONAMIDE, P-HYDROXY-N-2-PYRIMIDINYL-
Systematic Name English
N-(2-PYRIMIDINYL)-1-PHENOL-4-SULFONAMIDE
Systematic Name English
Code System Code Type Description
FDA UNII
YX560LZ60W
Created by admin on Mon Mar 31 19:25:57 GMT 2025 , Edited by admin on Mon Mar 31 19:25:57 GMT 2025
PRIMARY
CAS
20778-16-9
Created by admin on Mon Mar 31 19:25:57 GMT 2025 , Edited by admin on Mon Mar 31 19:25:57 GMT 2025
PRIMARY
EPA CompTox
DTXSID60174857
Created by admin on Mon Mar 31 19:25:57 GMT 2025 , Edited by admin on Mon Mar 31 19:25:57 GMT 2025
PRIMARY
PUBCHEM
193566
Created by admin on Mon Mar 31 19:25:57 GMT 2025 , Edited by admin on Mon Mar 31 19:25:57 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> METABOLITE