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Details

Stereochemistry ACHIRAL
Molecular Formula C34H29N7O
Molecular Weight 551.6404
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of A-6730

SMILES

O=C1NC2=CC=CC=C2N1C3CCN(CC4=CC=C(C=C4)C5=C(N=C6C=C7N=CNC7=CC6=N5)C8=CC=CC=C8)CC3

InChI

InChIKey=BIWGYFZAEWGBAL-UHFFFAOYSA-N
InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36)(H,39,42)

HIDE SMILES / InChI

Molecular Formula C34H29N7O
Molecular Weight 551.6404
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
58.0 nM [IC50]
210.0 nM [IC50]
2200.0 nM [IC50]
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:47:02 GMT 2023
Edited
by admin
on Sat Dec 16 18:47:02 GMT 2023
Record UNII
YX4CPQ6V6X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
A-6730
Code English
AKT-I 1,2
Code English
AKT-INHIBITOR-1-2
Common Name English
AKT INHIBITOR VIII
Common Name English
2H-BENZIMIDAZOL-2-ONE, 1,3-DIHYDRO-1-(1-((4-(6-PHENYL-1H-IMIDAZO(4,5-G)QUINOXALIN-7-YL)PHENYL)METHYL)-4-PIPERIDINYL)-
Common Name English
1,3-DIHYDRO-1-(1-((4-(6-PHENYL-1H-IMIDAZO(4,5-G)QUINOXALIN-7-YL)PHENYL)METHYL)-4-PIPERIDINYL)-2H-BENZIMIDAZOL-2-ONE
Common Name English
Code System Code Type Description
CAS
612847-09-3
Created by admin on Sat Dec 16 18:47:02 GMT 2023 , Edited by admin on Sat Dec 16 18:47:02 GMT 2023
PRIMARY
FDA UNII
YX4CPQ6V6X
Created by admin on Sat Dec 16 18:47:02 GMT 2023 , Edited by admin on Sat Dec 16 18:47:02 GMT 2023
PRIMARY
EPA CompTox
DTXSID50436572
Created by admin on Sat Dec 16 18:47:02 GMT 2023 , Edited by admin on Sat Dec 16 18:47:02 GMT 2023
PRIMARY