2,2',4,4',6-PENTABROMODIPHENYL ETHER

BrC1=CC=C(OC2=C(Br)C=C(Br)C=C2Br)C(Br)=C1

InChIKey=NSKIRYMHNFTRLR-UHFFFAOYSA-N

InChI=1S/C12H5Br5O/c13-6-1-2-11(8(15)3-6)18-12-9(16)4-7(14)5-10(12)17/h1-5H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Optimization of solid-phase microextraction for the gas chromatography/mass spectrometry analysis of persistent organic pollutants.	2004 Jul-Aug	15295899
Tissue disposition, excretion and metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) in male Sprague-Dawley rats.	2006 Jan	16507514
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.	2006 Jul	16601080
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.	2008 Apr	18324785
Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells.	2009 Aug	19672399
The sensitivity of the MDA-kb2 cell in vitro assay in detecting anti-androgenic chemicals--identification of sources of variability and estimation of statistical power.	2010 Sep	20488240
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.	2013 Mar 19	23398518
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.	2015 Apr 1	25680588
Primary role of cytochrome P450 2B6 in the oxidative metabolism of 2,2',4,4',6-pentabromodiphenyl ether (BDE-100) to hydroxylated BDEs.	2015 Apr 20	25629761

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 00:10:02 GMT 2023` Edited by `admin` on `Sat Dec 16 00:10:02 GMT 2023`
Record UNII	YW2W2K0A6U
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2,2',4,4',6-PENTABROMODIPHENYL ETHER

Common Name

English

BENZENE, 1,3,5-TRIBROMO-2-(2,4-DIBROMOPHENOXY)-

Systematic Name

English

PBDE 100

Common Name

English

Code System Code Type Description

CHEBI

138065