MAZORELVIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:31:00 GMT 2025` Edited by `admin` on `Tue Apr 01 23:31:00 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	YRJ2INY46N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAZORELVIMAB

Official Name

English

CTB-012

Preferred Name

English

SYN-023 COMPONENT CTB-012

Code

English

IMMUNOGLOBULIN G1, ANTI-(RABIES LYSSAVIRUS SPIKE GLYCOPROTEIN G) (HUMAN-MUS MUSCULUS CLONE 2G11 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS CLONE 2G11 .KAPPA.-CHAIN, DIMER

Common Name

English

mazorelvimab [INN]

Common Name

English

CTB012

Code

English

SYN023 COMPONENT CTB012

Code

English

Code System Code Type Description

NCI_THESAURUS

C184867

Created by admin on Tue Apr 01 23:31:00 GMT 2025 , Edited by admin on Tue Apr 01 23:31:00 GMT 2025

PRIMARY

CAS

2419087-89-9

Created by admin on Tue Apr 01 23:31:00 GMT 2025 , Edited by admin on Tue Apr 01 23:31:00 GMT 2025

PRIMARY

INN

11745

Created by admin on Tue Apr 01 23:31:00 GMT 2025 , Edited by admin on Tue Apr 01 23:31:00 GMT 2025

PRIMARY

FDA UNII

YRJ2INY46N

Created by admin on Tue Apr 01 23:31:00 GMT 2025 , Edited by admin on Tue Apr 01 23:31:00 GMT 2025

PRIMARY

SMS_ID

300000039100

Created by admin on Tue Apr 01 23:31:00 GMT 2025 , Edited by admin on Tue Apr 01 23:31:00 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_219
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199
1_223	3_219
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					QU56CN2GCO

RABIES VIRUS G GLYCOPROTEIN

TARGET -> INHIBITOR

Amount:


					I0V66KI1LD

TARGET ORGANISM->INHIBITOR

Amount:

Related Record Type Details


					YRJ2INY46N

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL