Amiquinsin hydrochloride was administered orally (10-40 mg/kg) to dogs as crystalline material in gelatin capsules. The drug was also administered parenterally (intravenously or intramuscularly, 2.5-10 mg/kg) to dogs as a solution in 5% dextrose, pH 4.4 to 4.8. Drug solutions were infused intravenously at a rate of 1.91 ml/min and at doses ranging from 1.25 to 10.00 mg/kg per hr using a Harvard pump.