Details
Stereochemistry | ACHIRAL |
Molecular Formula | C28H32N6 |
Molecular Weight | 452.5939 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 4 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C(\C)=N\C1=CC=C(C=C1)\N=C\C2=CC=C(C=C2)\C=N\C3=CC=C(C=C3)\N=C(/C)N(C)C
InChI
InChIKey=XOIOGKHKNQYULW-HTNNXBMUSA-N
InChI=1S/C28H32N6/c1-21(33(3)4)31-27-15-11-25(12-16-27)29-19-23-7-9-24(10-8-23)20-30-26-13-17-28(18-14-26)32-22(2)34(5)6/h7-20H,1-6H3/b29-19+,30-20+,31-21+,32-22+
Molecular Formula | C28H32N6 |
Molecular Weight | 452.5939 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 4 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
[Tribendimidine--a new broad-spectrum drug against intestinal helminths]. | 2004 Oct |
|
Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China. | 2005 Apr |
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Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. | 2005 Dec |
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[Development of novel antihelminthic therapies]. | 2006 Aug |
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Effect of tribendimidine on adult Echinostoma caproni harbored in mice, including scanning electron microscopic observations. | 2006 Aug |
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[Effect of a novel drug--enteric coated tribendimidine in the treatment of intestinal nematode infections]. | 2006 Feb 28 |
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New technologies for the control of human hookworm infection. | 2006 Jul |
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[Clinical observation on 899 children infected with intestinal nematodes and treated with tribendimidine enteric coated tablets]. | 2007 Oct |
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Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against Clonorchis sinensis: a comparative in vivo study. | 2008 Apr |
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Artemether and tribendimidine lack activity in experimental treatment of Paragonimus westermani in the dog. | 2008 Feb |
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[Tribendimidine enteric coated tablet in treatment of 1,292 cases with intestinal nematode infection--a phase IV clinical trial]. | 2008 Feb 28 |
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Opisthorchis viverrini: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro. | 2008 Mar |
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Developing novel anthelmintics from plant cysteine proteinases. | 2008 Sep 1 |
|
The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist. | 2009 Aug 11 |
|
Pharmacotherapy of helminth infection. | 2009 Feb |
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[Experimental study progress on tribendimidine, artemether and artesunate against Clonorchis sinensis and other trematodes]. | 2009 Feb 28 |
|
[Therapeutic effect of tribendimidine, artesunate and praziquantel administered to hamsters infected with Clonorchis sinensis]. | 2009 Jun |
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Metabolism and disposition of tribendimidine and its metabolites in healthy Chinese volunteers. | 2010 |
|
The drugs we have and the drugs we need against major helminth infections. | 2010 |
|
[Effect of six anthelmintics in oral treatment of mice infected with Armillifer agkistrodontis nymphs]. | 2010 Aug |
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[Efficacy of tribendimidine and albendazole in treating mice infected with Trichinella spiralis]. | 2010 Feb |
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[Treatment of rats infected with Clonorchis sinensis using clinical administration regimens of tribendimidine, praziquantel and artesunate]. | 2010 Jun 30 |
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The effect of tribendimidine and its metabolites against Necator americanus in golden hamsters and Nippostrongylus braziliensis in rats. | 2010 Mar |
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Bacillus thuringiensis Cry5B protein is highly efficacious as a single-dose therapy against an intestinal roundworm infection in mice. | 2010 Mar 2 |
|
"Manifesto" for advancing the control and elimination of neglected tropical diseases. | 2010 May 25 |
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Ascaris lumbricoides: an overview of therapeutic targets. | 2010 Oct |
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Update on the diagnosis and treatment of food-borne trematode infections. | 2010 Oct |
|
Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis. | 2010 Sep |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:22:56 GMT 2023
by
admin
on
Fri Dec 15 18:22:56 GMT 2023
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Record UNII |
YO6SOD6ZTJ
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Record Status |
Validated (UNII)
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Record Version |
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-
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3086564
Created by
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YO6SOD6ZTJ
Created by
admin on Fri Dec 15 18:22:56 GMT 2023 , Edited by admin on Fri Dec 15 18:22:56 GMT 2023
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Tribendimidine
Created by
admin on Fri Dec 15 18:22:56 GMT 2023 , Edited by admin on Fri Dec 15 18:22:56 GMT 2023
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DTXSID50894077
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admin on Fri Dec 15 18:22:56 GMT 2023 , Edited by admin on Fri Dec 15 18:22:56 GMT 2023
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115103-15-6
Created by
admin on Fri Dec 15 18:22:56 GMT 2023 , Edited by admin on Fri Dec 15 18:22:56 GMT 2023
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