U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:00:11 GMT 2023
Edited
by admin
on Sat Dec 16 15:00:11 GMT 2023
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
YNH9K62UXU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EFAVALEUKIN ALFA
USAN   INN  
Official Name English
Immunoglobulin G1 γ1-chain C-terminal constant region fragment (Fc) (1-226 without C-terminal Lys, N77G,D136E,L138M variant)-G4S linker (227-231)-human interleukin 2 (232-364, V322K,C356A variant) fusion protein, dimer disulfide, produced in Chinese ham
Systematic Name English
AMG 592
Code English
efavaleukin alfa [INN]
Common Name English
EFAVALEUKIN ALFA [USAN]
Common Name English
AMG-592
Code English
FC IL-2 MUTEIN FUSION PROTEIN (AMG-592)
Common Name English
IMMUNOGLOBULIN G1 (FC DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INTERLEUKIN 2 (SYNTHETIC HUMAN MUTEIN), DIMER
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 620217
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C169929
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
PRIMARY
FDA UNII
YNH9K62UXU
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
PRIMARY
CAS
2049067-94-7
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
PRIMARY
INN
10762
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
PRIMARY
USAN
GH-64
Created by admin on Sat Dec 16 15:00:11 GMT 2023 , Edited by admin on Sat Dec 16 15:00:11 GMT 2023
PRIMARY
From To
1_41 1_101
1_147 1_205
1_289 1_336
2_41 2_101
2_147 2_205
2_289 2_336
1_6 2_6
1_9 2_9
Related Record Type Details
TARGET -> AGONIST
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL