EFAVALEUKIN ALFA

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:48:29 GMT 2025` Edited by `admin` on `Wed Apr 02 02:48:29 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	YNH9K62UXU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMG 592

Preferred Name

English

EFAVALEUKIN ALFA

Official Name

English

Immunoglobulin G1 ?1-chain C-terminal constant region fragment (Fc) (1-226 without C-terminal Lys, N77G,D136E,L138M variant)-G4S linker (227-231)-human interleukin 2 (232-364, V322K,C356A variant) fusion protein, dimer disulfide, produced in Chinese hams

Systematic Name

English

Efavaleukin alfa [WHO-DD]

Common Name

English

efavaleukin alfa [INN]

Common Name

English

EFAVALEUKIN ALFA [USAN]

Common Name

English

AMG-592

Code

English

FC IL-2 MUTEIN FUSION PROTEIN (AMG-592)

Common Name

English

IMMUNOGLOBULIN G1 (FC DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INTERLEUKIN 2 (SYNTHETIC HUMAN MUTEIN), DIMER

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

620217