Emideltide or delta-sleep-inducing peptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) is a nonapeptide originally isolated from rabbit cerebral venous blood. It promotes sleep and this has been demonstrated in rabbits, mice, rats, cats and human beings. Emideltide showed significant and specific enhancement/induction of delta and spindle electroencephalogram patterns. In addition to sleep, the peptide also has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
Originator
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1299794
25 nmol/kg body weight
Route of Administration:
Intravenous
Substance Class |
Protein
Created
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Sat Dec 16 16:41:10 GMT 2023
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admin
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Sat Dec 16 16:41:10 GMT 2023
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Protein Type | PEPTIDE |
Protein Sub Type | |
Sequence Type | COMPLETE |
Record UNII |
YN28Z5YZ73
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Record Status |
Validated (UNII)
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WIKIPEDIA |
Designer-drugs-EMIDELTIDE
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NCI_THESAURUS |
C29756
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m4775
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C80673
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DTXSID20978151
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SUB06505MIG
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69431-45-4
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Delta-sleep-inducing peptide
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62568-57-4
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CHEMBL2104403
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68816
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YN28Z5YZ73
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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Molecular Formula | CHEMICAL |
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