MGS-0028

N[C@]1(CC(=O)[C@@H]2[C@H]1[C@@]2(F)C(O)=O)C(O)=O

InChIKey=KFAGJPNFERWZJA-JKBXLQNXSA-N

InChI=1S/C8H8FNO5/c9-8(6(14)15)3-2(11)1-7(10,4(3)8)5(12)13/h3-4H,1,10H2,(H,12,13)(H,14,15)/t3-,4-,7+,8-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Antipsychotic action of selective group II metabotropic glutamate receptor agonist MGS0008 and MGS0028 on conditioned avoidance responses in the rat.	2003-08-15	12875903
Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists.	2000-12-14	11123999

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:58:16 GMT 2025` Edited by `admin` on `Mon Mar 31 20:58:16 GMT 2025`
Record UNII	YMS878LR7I
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(+)-MGS-0028

Preferred Name

English

MGS-0028

Common Name

English

BICYCLO(3.1.0)HEXANE-2,6-DICARBOXYLIC ACID, 2-AMINO-6-FLUORO-4-OXO-, (1R,2S,5S,6S)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

9837317

Created by admin on Mon Mar 31 20:58:16 GMT 2025 , Edited by admin on Mon Mar 31 20:58:16 GMT 2025

PRIMARY

CAS

260353-67-1

Created by admin on Mon Mar 31 20:58:16 GMT 2025 , Edited by admin on Mon Mar 31 20:58:16 GMT 2025

SUPERSEDED

FDA UNII

YMS878LR7I

Created by admin on Mon Mar 31 20:58:16 GMT 2025 , Edited by admin on Mon Mar 31 20:58:16 GMT 2025

PRIMARY

CAS

321963-33-1

Created by admin on Mon Mar 31 20:58:16 GMT 2025 , Edited by admin on Mon Mar 31 20:58:16 GMT 2025

PRIMARY