Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C16H14O6 |
Molecular Weight | 302.2788 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12C3=CC(O)=C(O)C=C3C[C@@]1(O)COC4=C2C=CC(O)=C4O
InChI
InChIKey=WZUVPPKBWHMQCE-XJKSGUPXSA-N
InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
Molecular Formula | C16H14O6 |
Molecular Weight | 302.2788 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Hematoxylin staining is a well-established technique in histopathology and cytology for the diagnosis of malignant and non-malignant lesions. This compound forms strongly colored complexes with Fe(III) and Al(III) salts. Hematoxylin can be used as a primary stain and as a counterstain where it will differentiate acidophilic materials from basophilic materials and stain non-cellular substances such as fibrin, crystals, and pigments in various shades depending on the nature of the mordant used and the second stain.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: Fe(III) Sources: https://www.ncbi.nlm.nih.gov/pubmed/17835871 |
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Target ID: aluminium (III) Sources: https://www.ncbi.nlm.nih.gov/pubmed/94723 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Diagnostic | Unknown Approved UseUnknown |
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Diagnostic | Unknown Approved UseUnknown |
PubMed
Title | Date | PubMed |
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Unpredicted spontaneous extrusion of a renal calculus in an adult male with spina bifida and paraplegia: report of a misdiagnosis. Measures to be taken to reduce urological errors in spinal cord injury patients. | 2001 |
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Tumour necrosis factor-alpha production in fibrosing alveolitis is macrophage subset specific. | 2001 |
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A prospective randomised study of laser reshaping of cartilage in vivo. | 2001 |
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Electrolytic ablation of the rat pancreas: a feasibility trial. | 2001 |
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Non-detection of Chlamydia species in carotid atheroma using generic primers by nested PCR in a population with a high prevalence of Chlamydia pneumoniae antibody. | 2001 |
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Potential role and chronology of abnormal expression of the Deleted in Colon Cancer (DCC) and the p53 proteins in the development of gastric cancer. | 2001 |
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Loss of kidney IGF-1 receptors in experimental long-term diabetic rats. | 2001 Aug |
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The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems. | 2001 Aug |
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Telomerase activity and patient survival after surgery for gastric and oesophageal cancer. | 2001 Aug |
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Zonal dermal separation: a distinctive histopathological lesion associated with hyperelastosis cutis in a Quarter Horse. | 2001 Aug |
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Histopathological study of feline eosinophilic dermatoses. | 2001 Dec |
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[Glycogen-rich clear-cell breast carcinoma with neuroendocrine differentiation features]. | 2001 Dec |
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In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. | 2001 Dec |
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Myointimal hyperplasia and sympathetic reinnervation following local cold injury and rapid rewarming in the rabbit central ear artery. | 2001 Jul |
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The effect of tibial lengthening using the Ilizarov method on the cartilage and the menisci of the knee joint. | 2001 Jul |
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Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype. | 2001 Jun |
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Vascularized peripheral nerve trunk autografted in the spinal cord: a new experimental model in adult rats. | 2001 Nov |
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A pathological study of tumour regression in oesophageal adenocarcinoma treated with preoperative chemoradiotherapy. | 2001 Nov |
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The effect of Senecio latifolius a plant used as a South African traditional medicine, on a human hepatoma cell line. | 2001 Nov |
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Localization of keratan sulphate and chondroitin-6-sulphate on the anteriorly displaced human temporomandibular joint disc--histological and immunohistochemical analysis. | 2001 Oct |
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Assessment of right ventricular lipomatosis by histomorphometry in control adult autopsy cases. | 2001 Oct |
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The effect of a reconstituted basement membrane (matrigel) on a human salivary gland myoepithelioma cell line. | 2001 Oct |
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Morphometric analysis of the intestine of domestic quails (Coturnix coturnix japonica) treated with different levels of dietary calcium. | 2001 Oct |
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A study of four cases of extra-orbital giant cell angiofibroma with documentation of some unusual features. | 2001 Oct |
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Extent of ductal carcinoma in situ within and surrounding invasive primary breast carcinoma. | 2001 Oct |
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Helicobacter heilmannii gastritis: a histological and immunohistochemical trait. | 2001 Oct |
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Bone marrow trephine biopsy. | 2001 Oct |
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Arterial changes in paediatric haemodialysis patients undergoing renal transplantation. | 2001 Oct |
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Evaluation of functional response of cerebral arteries by a new morphometric technique. | 2001 Oct 8 |
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Cilia-Associated Respiratory (CAR) bacillus infection in veal calves and adult cattle. | 2001 Sep |
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Histological findings of surgically excised choroidal neovascular membranes after photodynamic therapy. | 2001 Sep |
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Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis. | 2002 Feb 1 |
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Prerequisites for effective adenovirus mediated gene therapy of colorectal liver metastases in the rat using an intracellular neutralizing antibody fragment to p21-Ras. | 2002 Feb 1 |
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Occult axillary lymph node metastases are of no prognostic significance in breast cancer. | 2002 Feb 1 |
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Abnormal FHIT expression profiles in cervical intraepithelial neoplastic (CIN) lesions. | 2002 Feb 1 |
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Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor. | 2002 Feb 12 |
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A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma. | 2002 Feb 12 |
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Accelerated hyperfractionation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation. | 2002 Feb 12 |
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Sentinel lymph node biopsy and breast cancer. | 2002 Jan |
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Conclusions from a study of venous invasion in stage IV colorectal adenocarcinoma. | 2002 Jan |
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Subglottic stenosis after endolaryngeal intubation in infants and children: result of wound healing processes. | 2002 Jan 11 |
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Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8. | 2002 Jan 21 |
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Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. | 2002 Jan 21 |
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E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia. | 2002 Jan 21 |
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Prognostic significance of dihydropyrimidine dehydrogenase expression in breast cancer. | 2002 Jan 21 |
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17beta-Oestradiol treatment modulates nitric oxide synthase activity in MDA231 tumour with implications on growth and radiation response. | 2002 Jan 7 |
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Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo. | 2002 Jan 7 |
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Feline leprosy: two different clinical syndromes. | 2002 Mar |
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Analysis of CHK2 in vulval neoplasia. | 2002 Mar 4 |
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An analysis of p53, BAX and vascular endothelial growth factor expression in node-positive rectal cancer. Relationships with tumour recurrence and event-free survival of patients treated with adjuvant chemoradiation. | 2002 Mar 4 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:34:55 UTC 2023
by
admin
on
Fri Dec 15 15:34:55 UTC 2023
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Record UNII |
YKM8PY2Z55
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C461
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YKM8PY2Z55
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8005-33-2
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SUB178443
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51686
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m5942
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Haematoxylin
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100000164077
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DTXSID8020678
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208-237-3
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442514
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90116
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517-28-2
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4174
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C75425
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232-337-6
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270085
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