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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H22N2S.ClH
Molecular Weight 334.907
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIMEPRAZINE HYDROCHLORIDE, (R)-

SMILES

Cl.C[C@H](CN(C)C)CN1C2=CC=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=QUVSTPKPFAPBQU-PFEQFJNWSA-N
InChI=1S/C18H22N2S.ClH/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;/h4-11,14H,12-13H2,1-3H3;1H/t14-;/m1./s1

HIDE SMILES / InChI

Molecular Formula C18H22N2S
Molecular Weight 298.446
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
One thousand small-bowel biopsies in children. A single-port versus a double-port capsule.
2001 Nov
Acute fatal poisoning with cyamemazine.
2003 Oct 14
Interspecies variability and drug interactions of loxapine metabolism in liver microsomes.
2003 Oct-Dec
Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis: reversal of migration order.
2003 Sep
Effectiveness of alimemazine in controlling retching after Nissen fundoplication.
2005 Nov
Behavioral treatment of bedtime problems and night wakings in infants and young children.
2006 Oct
Trypanosoma cruzi dihydrolipoamide dehydrogenase as target for phenothiazine cationic radicals. Effect of antioxidants.
2006 Sep
Drop-to-drop solvent microextraction coupled with gas chromatography/mass spectrometry for rapid determination of trimeprazine in urine and blood of rats: application to pharmacokinetic studies.
2007
Large-scale identification of human genes implicated in epidermal barrier function.
2007
Evaluation of enantioselective binding of basic drugs to plasma by ACE.
2007 Aug
Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents.
2007 Dec
Enantioseparation of phenotiazines by affinity electrokinetic chromatography using human serum albumin as chiral selector: application to enantiomeric quality control in pharmaceutical formulations.
2007 Jan 23
Up-regulation of loricrin expression by cell adhesion molecule nectin-1 through Rap1-ERK signaling in keratinocytes.
2007 Jun 22
Enantioseparation of phenothiazines in CD-modified CZE using single isomer sulfated CD as a chiral selector.
2007 Nov
Quetiapine and drug interactions: evidence from a routine therapeutic drug monitoring service.
2007 Oct
A fixed dilated pupil: Pilocarpine: better than a scan.
2008 Jan 26
Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
2008 May 1
Simultaneous determination of some phenothiazine derivatives in human blood by headspace solid-phase microextraction and gas chromatography with nitrogen-phosphorus detection.
2008 Nov-Dec
[Is alimemazine a suitable sleeping agent for children?].
2008 Oct 9
Oral midazolam premedication for children undergoing general anaesthesia for dental care.
2009
Calcium-binding S100 protein expression in pterygium.
2009
Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly?
2009 Jun 4
Intracellular and Extracellular Effects of S100B in the Cardiovascular Response to Disease.
2010
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder.
2010 Feb 23
Web-based, participant-driven studies yield novel genetic associations for common traits.
2010 Jun 24
Refractory agitation as a marker for pediatric delirium in very young infants at a pediatric intensive care unit.
2010 Nov
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:14:43 GMT 2023
Edited
by admin
on Sat Dec 16 05:14:43 GMT 2023
Record UNII
YKL63XT90B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIMEPRAZINE HYDROCHLORIDE, (R)-
Common Name English
10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, HYDROCHLORIDE (1:1), (R)-
Systematic Name English
ALIMEMAZINE HYDROCHLORIDE, (R)-
Common Name English
Code System Code Type Description
PUBCHEM
76965887
Created by admin on Sat Dec 16 05:14:43 GMT 2023 , Edited by admin on Sat Dec 16 05:14:43 GMT 2023
PRIMARY
FDA UNII
YKL63XT90B
Created by admin on Sat Dec 16 05:14:43 GMT 2023 , Edited by admin on Sat Dec 16 05:14:43 GMT 2023
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER