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Details

Stereochemistry ACHIRAL
Molecular Formula C5H8FNO2
Molecular Weight 133.1209
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUCICLOVINE

SMILES

N[C@]1(C[C@H](F)C1)C(O)=O

InChI

InChIKey=NTEDWGYJNHZKQW-IWLYVCSRSA-N
InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-

HIDE SMILES / InChI

Molecular Formula C5H8FNO2
Molecular Weight 133.1209
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

FLUCICLOVINE is a synthetic amino acid which is transported across mammalian cell membranes by amino acid transporters such as LAT-1 and ASCT2. Its 18F radiolabelled form is a positron emission tomography (PET) tracer targeting prostate cancer cells where aforementioned transporters are known to be upregulated, providing a mechanism for the enhanced accumulation of the tracer in these cells.

Approval Year

PubMed

Substance Class Chemical
Record UNII
YKG0YF688X
Record Status Validated (UNII)
Record Version