CLOMETOCILLIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	EPIMERIC
Molecular Formula	C17H18Cl2N2O5S
Molecular Weight	433.306
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLOMETOCILLIN

Structure Search

SMILES

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(OC)C3=CC=C(Cl)C(Cl)=C3)C(O)=O

InChI

InChIKey=JKXQBIZCQJLVOS-GSNLGQFWSA-N

InChI=1S/C17H18Cl2N2O5S/c1-17(2)12(16(24)25)21-14(23)10(15(21)27-17)20-13(22)11(26-3)7-4-5-8(18)9(19)6-7/h4-6,10-12,15H,1-3H3,(H,20,22)(H,24,25)/t10-,11?,12+,15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H18Cl2N2O5S
Molecular Weight	433.306
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	3 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14145726 | https://www.ncbi.nlm.nih.gov/pubmed/9578165

Clometocillin, one of the forms of penicillin, was active against pen-I or pen-R pneumococci and was used in children. The modern information about its application is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[USE IN CHILDREN OF A NEW ORAL PENICILLIN: CLOMETOCILLIN].	1964 Apr 25	14145726
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.	1998 Mar	9578165

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:41:59 GMT 2023` Edited by `admin` on `Fri Dec 15 17:41:59 GMT 2023`
Record UNII	YI8LL014GF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOMETOCILLIN

Official Name

English

(3,4-DICHLORO-.ALPHA.-METHOXYBENZYL)PENICILLIN

Common Name

English

clometocillin [INN]

Common Name

English

Clometocillin [WHO-DD]

Common Name

English

CLOMETOCILLIN [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1500

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

WHO-VATC

QJ01CE07

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

WHO-ATC

J01CE07

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

Code System Code Type Description

FDA UNII

YI8LL014GF

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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EPA CompTox

DTXSID20172859

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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WIKIPEDIA

Clometocillin

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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SMS_ID

100000084544

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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MERCK INDEX

m3646

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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Merck Index

CAS

1926-49-4

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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INN

1326

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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DRUG CENTRAL

699

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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EVMPD

SUB06721MIG

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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ChEMBL

CHEMBL2106548

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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DRUG BANK

DB13686

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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ECHA (EC/EINECS)

217-657-6

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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NCI_THESAURUS

C76221

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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PUBCHEM

71807

Created by admin on Fri Dec 15 17:41:59 GMT 2023 , Edited by admin on Fri Dec 15 17:41:59 GMT 2023

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