Posnafusp Alfa

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:03:47 GMT 2025` Edited by `admin` on `Wed Apr 02 20:03:47 GMT 2025`
Protein Type	FUSION PROTEINS
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	YF3FFU3WCF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1 Fab fragment, anti-(human transferrin receptor) (human-Mus musculus monoclonal JR-441 ?1-chain) fusion protein with peptide linker (GGGGS)3 fusion protein with human N-sulfoglucosamine sulfohydrolase, disulfide with human-Mus musculus m

Preferred Name

English

Posnafusp Alfa

Official Name

English

gamma 1 heavy Fab chain (1-226) [VH (Homo sapiens IGHV5-51*01 -(IGHD) -IGHJ4*01, CDR-Kabat [5.17.9] (31-35.50-66.99-107)) (1-118) -Homo sapiens IGHG1*01 (CH1 (119-226)] fused via peptide linker <sup>227</sup> GGGGSGGGGSGGGGS <sup>241</sup> to N-sulphoglu

Common Name

English

posnafusp alfa [INN]

Common Name

English

humanized immunoglobulin G1-kappa antigen-binding fragment (Fab), anti-[human transferrin receptor 1 (hTfR, p90, CD71)] fused at the C-terminus of the heavy chain via a peptide linker to human N-sulphoglucosamine sulphohydrolase (SGSH, sulfoglucosamine s

Common Name

English

Code System Code Type Description

FDA UNII

YF3FFU3WCF