Armocibart

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:16:16 GMT 2025` Edited by `admin` on `Wed Apr 02 20:16:16 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Type	COMPLETE
Record UNII	YDG29RXC35
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

armocibart [INN]

Preferred Name

English

Armocibart

Official Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens TFPI (tissue factor pathway inhibitor, extrinsic pathway inhibitor, EPI, lipoprotein associated coagulation inhibitor, LACI)]

Common Name

English

Code System Code Type Description

INN

13116

Created by admin on Wed Apr 02 20:16:16 GMT 2025 , Edited by admin on Wed Apr 02 20:16:16 GMT 2025

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FDA UNII

YDG29RXC35

Created by admin on Wed Apr 02 20:16:16 GMT 2025 , Edited by admin on Wed Apr 02 20:16:16 GMT 2025

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SMS_ID

300000056807

Created by admin on Wed Apr 02 20:16:16 GMT 2025 , Edited by admin on Wed Apr 02 20:16:16 GMT 2025

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NCI_THESAURUS

C211828

Created by admin on Wed Apr 02 20:16:16 GMT 2025 , Edited by admin on Wed Apr 02 20:16:16 GMT 2025

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CAS

2857858-84-3

Created by admin on Wed Apr 02 20:16:16 GMT 2025 , Edited by admin on Wed Apr 02 20:16:16 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_135	4_219
2_148	2_204
2_262	2_322
1_135	3_219
2_368	2_426
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199
1_148	1_204
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					YDG29RXC35

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_448] [2_448]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL