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Details

Stereochemistry EPIMERIC
Molecular Formula C20H29NO3.ClH
Molecular Weight 367.91
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPENZOLATE HYDROCHLORIDE

SMILES

Cl.CN1CCC[C@H](C1)OC(=O)C(O)(C2CCCCC2)C3=CC=CC=C3

InChI

InChIKey=LBKCCRHBZAWYOP-HUVSLODASA-N
InChI=1S/C20H29NO3.ClH/c1-21-14-8-13-18(15-21)24-19(22)20(23,16-9-4-2-5-10-16)17-11-6-3-7-12-17;/h2,4-5,9-10,17-18,23H,3,6-8,11-15H2,1H3;1H/t18-,20?;/m1./s1

HIDE SMILES / InChI

Molecular Formula C20H29NO3
Molecular Weight 331.4492
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Propenzolate is a pyridine derivative patented by National Research Development Corp. as an anticholinergic agent. Propenzolate is effective antidotes to the cholinesterase-inhibiting action of various organophosphorus compounds. In clinical trials, Propenzolate has an activity that decreases to some extent the secretion of hydrochloric acid and the volume of gastric juice. Adverse effects, including nausea, vomiting, weakness, and drowsiness, as well as xerostomia and cycloplegia, are observed in a high percentage of patients receiving 0.5 to 1.0 mg. every 12 hours.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
0.5 to 1.0 mg. every 12 hours.
Route of Administration: Oral
Substance Class Chemical
Record UNII
YCZ9J99C72
Record Status Validated (UNII)
Record Version