ABT-255

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24FN3O3.ClH
Molecular Weight	421.893
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[H][C@]12CN(C[C@@]1([H])NCCC2)C3=C(C)C4=C(C=C(C(O)=O)C(=O)N4C=C3F)C5CC5

InChI

InChIKey=UTKJBXOVMQXMOU-OZIFAFRSSA-N

InChI=1S/C21H24FN3O3.ClH/c1-11-18-14(12-4-5-12)7-15(21(27)28)20(26)25(18)9-16(22)19(11)24-8-13-3-2-6-23-17(13)10-24;/h7,9,12-13,17,23H,2-6,8,10H2,1H3,(H,27,28);1H/t13-,17+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C21H24FN3O3
Molecular Weight	385.432
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
The health status of paramedics children in Dr. Pirngadi Hospital Medan, Indonesia.	1985 Nov-Dec	4094781
In vivo efficacy of ABT-255 against drug-sensitive and -resistant Mycobacterium tuberculosis strains.	1998 Oct	9756775
The 2-pyridone antibacterial agents: 8-position modifications.	1999 Jul	10438895
The 2-pyridone antibacterial agents: bacterial topoisomerase inhibitors.	2000 Jul	10861727

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:34:52 GMT 2023` Edited by `admin` on `Sat Dec 16 08:34:52 GMT 2023`
Record UNII	YA04O24J4T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABT-255

Common Name

English

4H-QUINOLIZINE-3-CARBOXYLIC ACID, 1-CYCLOPROPYL-7-FLUORO-9-METHYL-8-((4AS,7AS)-OCTAHYDRO-6H-PYRROLO(3,4-B)PYRIDIN-6-YL)-4-OXO-, MONOHYDROCHLORIDE

Systematic Name

English

4H-QUINOLIZINE-3-CARBOXYLIC ACID, 1-CYCLOPROPYL-7-FLUORO-9-METHYL-8-(OCTAHYDRO-6H-PYRROLO(3,4-B)PYRIDIN-6-YL)-4-OXO-, MONOHYDROCHLORIDE, (4AS-CIS)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID50939412

Created by admin on Sat Dec 16 08:34:52 GMT 2023 , Edited by admin on Sat Dec 16 08:34:52 GMT 2023

PRIMARY

PUBCHEM

9823540

Created by admin on Sat Dec 16 08:34:52 GMT 2023 , Edited by admin on Sat Dec 16 08:34:52 GMT 2023

PRIMARY

CAS

181141-52-6

Created by admin on Sat Dec 16 08:34:52 GMT 2023 , Edited by admin on Sat Dec 16 08:34:52 GMT 2023

PRIMARY

FDA UNII

YA04O24J4T

Created by admin on Sat Dec 16 08:34:52 GMT 2023 , Edited by admin on Sat Dec 16 08:34:52 GMT 2023

PRIMARY

Related Record Type Details


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