U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 14:58:53 GMT 2023
Edited
by admin
on Sat Dec 16 14:58:53 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family Rhabdoviridae
Organism Genus Vesiculovirus
Organism Species vesicular stomatitis indiana virus
Author NONE
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name rVSVΔG-ZEBOV-GP
Part WHOLE
Record UNII
Y9VG7O3KTT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RECOMBINANT ZAIRE EBOLAVIRUS KIKWIT-95 ENVELOPE GLYCOPROTEIN MODIFIED VESICULAR STOMATITIS VIRUS
Common Name English
RVSV.DELTA.G-ZEBOV-GP
Common Name English
V920
Code English
rVSVΔG-ZEBOV
Common Name English
rVSV-ZEBOV-GP
Common Name English
V-920
Code English
Code System Code Type Description
FDA UNII
Y9VG7O3KTT
Created by admin on Sat Dec 16 14:58:54 GMT 2023 , Edited by admin on Sat Dec 16 14:58:54 GMT 2023
PRIMARY
CLINICAL_TRIALS.GOV
NCT02283099
Created by admin on Sat Dec 16 14:58:54 GMT 2023 , Edited by admin on Sat Dec 16 14:58:54 GMT 2023
PRIMARY
Related Record Type Details
EXPRESSED PROTEIN->VECTOR
TARGET ORGANISM->VACCINE ANTIGEN
TARGET ORGANISM->VACCINE ANTIGEN

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE FRAGMENT REPLACEMENT EBOLA VIRUS/H. SAPIENS-TC/COD/1995/KIKWIT-9510622 ENVELOPE GLYCOPROTEIN GENE (VIRAL NEGATIVE STRAND) P7ZRG1LJ3A
GENE DELETION VESICULAR STOMATITIS INDIANA VIRUS VSIVGP4 GLYCOPROTEIN (G PROTEIN) PRECURSOR GENE E6TJ0Z0ZE8
VECTOR EXPRESSED PROTEIN VIRAL MEMBRANE ZAIRE EBOLAVIRUS STRAIN KIKWIT-95 ENVELOPE GLYCOPROTEIN XH5V2SQ5FI