U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 17:16:00 GMT 2023
Edited
by admin
on Sat Dec 16 17:16:00 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependovirus
Organism Species adeno-associated virus
Author NONE
Infraspecific Type SUBSTRAIN
Infraspecific Name AAVrh8-HEXA
Part WHOLE
Record UNII
Y92LXG5D7W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
COBNABEXAGENE ANVUPARVOVEC HEXA
Common Name English
AXO-AAV-GM2 COMPONENT AAVRH8-HEXA
Code English
AAVRH8-HEXA
Code English
COBNABEXAGENE ANVUPARVOVEC HEXA [USAN]
Common Name English
AAVRH8-HEXA (CONTAINS THE TRANSGENE WTHEXA WHICH ENCODES THE .BETA.-HEXOSAMINIDASE A PROTEIN)
Common Name English
Code System Code Type Description
NCI_THESAURUS
C188661
Created by admin on Sat Dec 16 17:16:00 GMT 2023 , Edited by admin on Sat Dec 16 17:16:00 GMT 2023
PRIMARY
FDA UNII
Y92LXG5D7W
Created by admin on Sat Dec 16 17:16:00 GMT 2023 , Edited by admin on Sat Dec 16 17:16:00 GMT 2023
PRIMARY
Related Record Type Details
TARGET->ENZYME REPLACEMENT
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR COBNABEXAGENE ANVUPARVOVEC A TRANSGENE INSERT L5JGZ2SF2Z