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Approval Year

Substance Class Protein
Created
by admin
on Sun Jun 27 00:41:43 UTC 2021
Edited
by admin
on Sun Jun 27 00:41:43 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
Y83809589C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THIAMINE TRANSPORTER 2
Common Name English
THTR-2
Common Name English
TRANSPORT PROTEIN SLC19A3 (HUMAN)
Common Name English
SOLUTE CARRIER FAMILY 19 MEMBER 3
Common Name English
THTR2
Common Name English
SLC19A3
Common Name English
Code System Code Type Description
CAS
479887-06-4
Created by admin on Sun Jun 27 00:41:43 UTC 2021 , Edited by admin on Sun Jun 27 00:41:43 UTC 2021
ALTERNATIVE
CAS
348644-19-9
Created by admin on Sun Jun 27 00:41:43 UTC 2021 , Edited by admin on Sun Jun 27 00:41:43 UTC 2021
PRIMARY
UNIPROT
Q9BZV2
Created by admin on Sun Jun 27 00:41:43 UTC 2021 , Edited by admin on Sun Jun 27 00:41:43 UTC 2021
PRIMARY
WIKIPEDIA
SLC19A3
Created by admin on Sun Jun 27 00:41:43 UTC 2021 , Edited by admin on Sun Jun 27 00:41:43 UTC 2021
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_45
N 1_166
Related Record Type Details
NON-INHIBITOR -> TRANSPORTER
GREATER THAN 100 MICROMOLAR
IC50
INHIBITOR -> TRANSPORTER
Patients being treated with fedratinib developed Wernicke?s encephalopathy (WE) (Sanofi, 2013), a neurological disorder linked to thiamine deficiency (Cook et al., 1998).
IC50
NON-INHIBITOR -> TRANSPORTER
IC50
INHIBITOR -> TRANSPORTER
IC50
SUBSTRATE -> TRANSPORTER
thiamine uptake in the hTHTR1and hTHTR2-transfected cells were 1.85 μM and 7.29 pmol/mg protein/min, and 3.28 μM and 35.0 pmol/mg protein/min,
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL