Tidagixagene Derxeparvovec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 15:40:42 GMT 2025` Edited by `admin` on `Wed Apr 02 15:40:42 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependoparvovirus
Organism Species	adeno-associated dependoparvovirus a
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	scAAV9/Synthetic JeT promoter/human codon-optimized gigaxonin/AAV2 inverted terminal repeats
Part	whole
Record UNII	Y7ARS22SWQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DNA (recombinant adeno-associated virus 9 vector TSHA-120 synthetic JeT promoter plus human gigaxonin transgene plus synthetic polyadenylation signal plus adeno-associated virus 2 inverted terminal repeat flanks-specifying)

Preferred Name

English

Tidagixagene Derxeparvovec

Official Name

English

TSHA-120

Common Name

English

recombinant, self-complementary (dimeric), non-replicating adeno-associated virus serotype 9 (scAAV9) vector encoding codon-optimised human gigaxonin (giant axonal neuropathy [GAN] gene, Kelch-like protein 16) under the control of the artificial JeT prom

Common Name

English

tidagixagene derxeparvovec [INN]

Common Name

English

Code System Code Type Description

FDA UNII

Y7ARS22SWQ