Ninsipapogene Sibarnarepvec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 16:36:25 GMT 2023` Edited by `admin` on `Sat Dec 16 16:36:25 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family	Arenaviridae
Infraspecific Type	SUBSTRAIN
Infraspecific Name	r3PICV-E7E6
Part	whole
Record UNII	Y70X1GJT61
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ninsipapogene Sibarnarepvec

Common Name

English

Recombinant replication-competent attenuated arenavirus (Pichinde virus [PICV]) vector with two copies of the small (S) genome segment (S RNA segment) with one encoding the viral membrane glycoprotein (GP) and one encoding the viral nucleocapsid protein

Common Name

English

RNA (attenuated replicating Pichinde virus vector HB-202 segment L), supramolecular complex with RNA (attenuated replicating Pichinde virus vector HB-202 segment S2 human papillomavirus 16 [24-glycine,26-glycine,91-glycine] gene E7 protein fusion protein

Common Name

English

NINSIPAPOGENE SIBARNAREPVEC [USAN]

Common Name

English

Code System Code Type Description

FDA UNII

Y70X1GJT61

Created by admin on Sat Dec 16 16:36:25 GMT 2023 , Edited by admin on Sat Dec 16 16:36:25 GMT 2023

PRIMARY

USAN

LM-174

Created by admin on Sat Dec 16 16:36:25 GMT 2023 , Edited by admin on Sat Dec 16 16:36:25 GMT 2023

PRIMARY

CAS

2640294-04-6

Created by admin on Sat Dec 16 16:36:25 GMT 2023 , Edited by admin on Sat Dec 16 16:36:25 GMT 2023

PRIMARY

INN

12223

Created by admin on Sat Dec 16 16:36:25 GMT 2023 , Edited by admin on Sat Dec 16 16:36:25 GMT 2023

PRIMARY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					Pichinde virus [PICV] vector HB-202 segment L (Ninsipapogene sibarnarepvec)	B7H6QP6UVF
INSERTED GENE EXPRESSION VECTOR					Pichinde virus [PICV] vector HB-202 segment S-2 (Ninsipapogene sibarnarepvec)	G9P78RFU5Y