U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula O2Si.H2O
Molecular Weight 78.0996
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDRATED SILICA

SMILES

O.O=[Si]=O

InChI

InChIKey=LRCFXGAMWKDGLA-UHFFFAOYSA-N
InChI=1S/O2Si.H2O/c1-3-2;/h;1H2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
MOL RATIO [0.25 to 2] MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula O2Si
Molecular Weight 60.0843
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Silicon dioxide (silica) is most commonly found in nature as quartz, as well as in various living organisms. Silicon dioxide one of the most complex and most abundant families of materials, existing both as several minerals and being produced synthetically. In food and pharmaceutical industry silica is a common additive, where it is used primarily as a flow in powdered foods, or to adsorb water in hygroscopic application. In pharmaceutical products, silica aids powder flow when tablets are formed.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Oxycodone Hydrochloride
Primary
Silicol gel
Primary
GELUSIL

PubMed

Sample Use Guides

In Vivo Use Guide
To treat gastrointestinal disorders, take one tablespoon (15ml) of silicol®gel (containing silicic acid which is a compound of silicon and oxygen) three times daily, preferably before mealtimes. After acute symptoms ease, treatment is recommended for another few days. For chronic conditions, treat for up to four weeks and then take a break to re-assess symptoms.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
Y6O7T4G8P9
Record Status Validated (UNII)
Record Version