TEPROTUMUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:44:02 GMT 2025` Edited by `admin` on `Mon Mar 31 20:44:02 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	Y64GQ0KC0A
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

TEPROTUMUMAB

Official Name

English

R-1507

Preferred Name

English

RG-1507

Code

English

Teprotumumab [WHO-DD]

Common Name

English

teprotumumab [INN]

Common Name

English

HZN-001

Code

English

RG1507

Code

English

TEPROTUMUMAB [MI]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (CD221)), HUMAN MONOCLONAL IMC-11F8 .GAMMA.1 HEAVY CHAIN (221-215')-DISULFIDE WITH HUMAN MONOCLONAL IMC-11F8 .KAPPA. LIGHT, DIMER (227-227'':230-230'')-BISDISULFIDE

Common Name

English

RO-4858696-000

Code

English

RO-4858696000

Code

English

RO-4858696

Code

English

HZN001

Code

English

TEPROTUMUMAB [USAN]

Common Name

English

RV001 MONOCLONAL

Code

English

RO4858696-000

Code

English

RO4858696

Code

English

RV-001 MONOCLONAL

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INSULIN-LIKE GROWTH FACTOR I RECEPTOR) (HUMAN MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LIGHT CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

FDA ORPHAN DRUG

387812

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

Code System Code Type Description

RXCUI

2274803

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

MERCK INDEX

m12242

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

CAS

1036734-93-6

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

FDA UNII

Y64GQ0KC0A

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

WIKIPEDIA

TEPROTUMUMAB

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

SMS_ID

100000164227

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

EVMPD

SUB178558

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

CAS

1422662-75-6

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

NO STRUCTURE GIVEN

USAN

XX-19

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

DRUG CENTRAL

5387

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

DAILYMED

Y64GQ0KC0A

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

NCI_THESAURUS

C95797

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

RXCUI

2274802

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

ALTERNATIVE

ChEMBL

CHEMBL1743079

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

DRUG BANK

DB06343

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

INN

9107

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

ECHA (EC/EINECS)

289-554-4

Created by admin on Mon Mar 31 20:44:02 GMT 2025 , Edited by admin on Mon Mar 31 20:44:02 GMT 2025

PRIMARY

From	To
1_22	1_96
1_145	1_201
1_221	3_215
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426
2_22	2_96
2_145	2_201
2_221	4_215
2_262	2_322
2_368	2_426
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					DK7PL4F3TT

INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR

TARGET -> INHIBITOR

Amount:

TEPROTUMUMAB-TRBW

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					Y64GQ0KC0A

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:ESTIMATE	CHEMICAL