DIOXOLANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H6O2
Molecular Weight	74.0785
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1COCO1

InChI

InChIKey=WNXJIVFYUVYPPR-UHFFFAOYSA-N

InChI=1S/C3H6O2/c1-2-5-3-4-1/h1-3H2

HIDE SMILES / InChI

Molecular Formula	C3H6O2
Molecular Weight	74.0785
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Partitioning behavior of an acid-cleavable, 1,3-dioxolane alkyl ethoxylate, surfactant in single and binary surfactant mixtures for 2- and 3-phase microemulsion systems according to ethoxylate head group size.	2010-12-15	20880539
tert-Butyl N-[(11-exo-benzyl-oxy-carbonyl-8-oxopenta-cyclo-[5.4.0.0.0.0]undecane-11-endo-yloxy)carbon-yl-methyl]carbamate.	2010-09-25	21587584
Synthesis and biological activity of N-substituted aminocarbonyl-1,3-dioxolanes as VLA-4 antagonists.	2010-09-15	20705461
New one-pot methodologies for the modification or synthesis of alkaloid scaffolds.	2010-08-24	20948914
A systematic study on the activation of simple polyethers by MoCl5 and WCl6.	2010-06-14	20454727
Intrinsic acidity and electrophilicity of gaseous propargyl/allenyl carbocations.	2010-06-07	20485794
Spiro-[1,3-dioxolane-2,3'-indolin]-2'-one.	2010-05-12	21579401
Novel anti-leukemia activities of pipoxolan operate via the mitochondria-related pathway in human leukemia U937 cells and attenuate U937 cell growth in an animal model.	2010-03-22	21472325
Exploring Morita-Baylis-Hillman reactions of p-quinols.	2010-02-05	20055444
Recent advances in synthetic bioelastomers.	2009-11-20	20057942
The reactivity of 1,1-dialkoxyalkanes with niobium and tantalum pentahalides. Formation of coordination compounds, C-H and C-C bond activation and the X-ray structure of the stable carboxonium species [Me(2)C=CHC(=OMe)Me][NbCl(5)(OMe)].	2009-10-14	19771374
Synthesis and X-ray structure of a C5-C4-linked glucofuranose-oxazolidin-2-one.	2009-10-12	19683708
3-(6-Benz-yloxy-2,2-dimethyl-perhydro-furo[2,3-d][1,3]dioxolan-5-yl)-5-(4-chloro-phen-yl)-4-nitro-2-phenyl-2,3,4,5-tetra-hydro-isoxazole.	2009-09-05	21577778
Biodegradability of plastics.	2009-08-26	19865515
Synthesis of uracil nucleotide analogs with a modified, acyclic ribose moiety as P2Y(2) receptor antagonists.	2009-07-15	19523835
Linking microscopic guest properties to macroscopic observables in clathrate hydrates: guest-host hydrogen bonding.	2009-05-07	19425784
2,3:4,6-Di-O-isopropylidene-alpha-L-sorbofuranose and 2,3-O-isopropylidene-alpha-L-sorbofuranose.	2009-04	19346611
Doubly diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters containing cis- and trans-dioxolane units.	2009-02-21	19194592
3-(1,3-Dioxolan-2-yl)-2-hydrazino-7-methyl-quinoline.	2009-01-28	21582000
The analysis of healthy volunteers' exhaled breath by the use of solid-phase microextraction and GC-MS.	2008-12	21386193
ZrCl4 as an efficient catalyst for a novel one-pot protection/deprotection synthetic methodology.	2008-08-15	18642872
Evaluation of a bromine-76-labeled progestin 16alpha,17alpha-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies.	2008-08	18678350
Reactivity of fullerene epoxide: preparation of fullerene-fused thiirane, tetrahydrothiazolidin-2-one, and 1,3-dioxolane.	2008-04-04	18336040
Molecular imaging as a tool for translating breast cancer science.	2008	19091007
Proton transfer in water wires in proteins: modulation by local constraint and polarity in gramicidin a channels.	2007-09-01	17496018
Applicability of fiber-optic-based Raman probes for on-line reaction monitoring of high-pressure catalytic hydrogenation reactions.	2007-05	17555615
New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance.	2007-03-15	17276076
Recent studies on reaction pathways and applications of sugar orthoesters in synthesis of oligosaccharides.	2007-02-26	17109835
A substrate-based folding process incorporating chemodifferentiating ABB' three-component reactions of terminal alkynoates and 1,2-dicarbonyl compounds: a skeletal-diversity-oriented synthetic manifold.	2007	17075926
Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.	2006-12-14	17149864
Rapid analysis of tile industry gaseous emissions by ion mobility spectrometry and comparison with solid phase micro-extraction/gas chromatography/mass spectrometry.	2006-12	17133278
Bromine- and iodine-substituted 16alpha,17alpha-dioxolane progestins for breast tumor imaging and radiotherapy: synthesis and receptor binding affinity.	2006-07-27	16854080
Distonoid ions.	2006-07	16713292
Inhibition of hepatitis B virus (HBV) replication by pyrimidines bearing an acyclic moiety: effect on wild-type and mutant HBV.	2006-03-23	16539393
Synthesis and anti-HSV-1 activity of quinolonic acyclovir analogues.	2006-02-15	16321530
Dehydroepiandrosterone sulfate and estrone sulfate reduce GABA-recurrent inhibition in the hippocampus via muscarinic acetylcholine receptors.	2006	17024678
Relationships between the structure of dexoxadrol and etoxadrol analogues and their NMDA receptor affinity.	2006	16719812
Structure-affinity relationship studies of non-competitive NMDA receptor antagonists derived from dexoxadrol and etoxadrol.	2005-12-15	16169732
Determination of 3-chloropropane-1,2-diol as its 1,3-dioxolane derivative at the microg kg-1 level: application to a wide range of foods.	2005-12	16356881
Ion/molecule reactions in a miniature RIT mass spectrometer.	2005-11	16255061
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives.	2005-06-01	15896343
Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs.	2004-12-01	15519166
Structural chemistry of new lithium bis(oxalato)borate solvates.	2004-12	15534382
Synthesis and biological activities of novel triazole compounds containing 1,3-dioxolane rings.	2004-11-30	18007492
Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats.	2004-11-15	15484303
Stereoselective photochemical 1,3-dioxolane addition to 5-alkoxymethyl-2(5H)-furanone: synthesis of bis-tetrahydrofuranyl ligand for HIV protease inhibitor UIC-94017 (TMC-114).	2004-11-12	15527257
Divergence of carbonyl ylide reactions as a function of diazocarbonyl compound and aldehyde substituent: dioxolanes, dioxolenes, and epoxides.	2004-08-06	15287769
Molecular mechanism of dioxolane nucleosides against 3TC resistant M184V mutant HIV.	2004-07	15196815
Fine-tuning monophosphine ligands for enhanced enantioselectivity. Influence of chiral hemilabile pendant groups.	2004-04-29	15101781
Surface tension and density of mixtures of 1,3-dioxolane+alkanols at 298.15 K: analysis under the extended Langmuir model.	2004-04-15	15028509

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:42:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:42:01 GMT 2025`
Record UNII	Y57RBG19JL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIOXOLANE

Official Name

English

1,3-DIOXOLANE

Preferred Name

English

ELCOTAL DX

Brand Name

English

1,3-DIOXACYCLOPENTANE

Systematic Name

English

1,3-DIOXOLANE [HSDB]

Common Name

English

GLYCOLFORMAL

Common Name

English

1,3-DIOXOLAN

Systematic Name

English

ETHYLENE GLYCOL FORMAL

Common Name

English

FORMAL GLYCOL

Common Name

English

5-CROWN-2

Common Name

English

DIOXOLANE, 1,3-

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

DIOXOLANE