U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 19:18:29 GMT 2023
Edited
by admin
on Sat Dec 16 19:18:29 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
Y5293N85Q7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Prafnosbart
INN  
Official Name English
DS-6016a
Code English
Immunoglobulin G1, anti-(human activin receptor-like kinase 2) (human-Rattus norvegicus monoclonal DS-6016a γ1-chain), disulfide with human-Rattus norvegicus monoclonal DS-6016a κ-chain, dimer
Common Name English
gamma1 heavy chain humanized (1-451) [VH humanized (Homo sapiens IGHV3-21*01 (88.7%) -(IGHD) -IGHJ4*01(93.3%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) - Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14 CH2 A1.3, A1.2 (CH1 R120 (218) (122-219), hinge 1-1
Common Name English
prafnosbart [INN]
Common Name English
immunoglobulin G1-kappa, anti-[Homo sapiens ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1)], humanized monoclonal antibody
Common Name English
Code System Code Type Description
INN
12177
Created by admin on Sat Dec 16 19:18:30 GMT 2023 , Edited by admin on Sat Dec 16 19:18:30 GMT 2023
PRIMARY
FDA UNII
Y5293N85Q7
Created by admin on Sat Dec 16 19:18:30 GMT 2023 , Edited by admin on Sat Dec 16 19:18:30 GMT 2023
PRIMARY
NCI_THESAURUS
C190498
Created by admin on Sat Dec 16 19:18:30 GMT 2023 , Edited by admin on Sat Dec 16 19:18:30 GMT 2023
PRIMARY
CAS
2566473-71-8
Created by admin on Sat Dec 16 19:18:30 GMT 2023 , Edited by admin on Sat Dec 16 19:18:30 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_148 2_204
2_224 4_214
2_265 2_325
1_148 1_204
2_371 2_429
3_23 3_87
3_134 3_194
4_23 4_87
4_134 4_194
1_224 3_214
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL