MANGANESE HYDROGEN CITRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H6O7.Mn
Molecular Weight	245.0457
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

[Mn++].OC(=O)C(O)(CC([O-])=O)CC([O-])=O

InChI

InChIKey=YKPGEBJMSSYKPC-UHFFFAOYSA-L

InChI=1S/C6H8O7.Mn/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+2/p-2

HIDE SMILES / InChI

Molecular Formula	Mn
Molecular Weight	54.938045
Charge	2
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H6O7
Molecular Weight	190.1076
Charge	-2
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Manganese Bromide is a highly water soluble crystalline salt composed of manganese and bromine with the formula MnBr2. Manganese Bromide can be used in place of palladium in the Stille reaction, which couples two carbon atoms using an organotin compound

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Arginase-1 25	Activator 1,447
Arginase-2, mitochondrial 24	Activator 1,447
Glutamine synthetase 29	Activator 1,447

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2,596
Unknown 2,596
Unknown 2,596
Cancer 609	Primary	Basic research	Unknown
Manganese deficiency 27	Primary	Approved 8,583	Unknown
Osteoporosis 101	Primary	Approved 8,583	Unknown
Premenstrual syndrome 38	Palliative	Approved 8,583	Unknown
Manganese deficiency 27	Curative	Approved 8,583	MANGANESE SULFATE
Unknown 2,596
Unknown 2,596
Gastrointestinal disorders 94	Primary	Approved 8,583	MANGANESE SULFATE

PubMed

Show entries

Title	Date	PubMed
Cytochrome oxidase determination using a manganese citrate complex.	1970	4322423
Metabolism of l-Tyrosine to 4-Hydroxybenzaldehyde and 3-Bromo-4-Hydroxybenzaldehyde by Chloroplast-containing Fractions of Odonthalia floccosa (Esp.) Falk.	1979 Dec	16661087
Effect of fluoride on copper, manganese and zinc in bone and kidney.	1981 Mar	7284642
Effect of quantity and route of administration of manganese monoxide on feed intake and serum manganese in ruminants.	1985 Feb	3989083
Dietary calcium and manganese effects on menstrual cycle symptoms.	1993 May	8498421

Showing 1 to 5 of 27 entries

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Sample Use Guides

In Vivo Use Guide

Broiler chicks:A basal corn-soybean meal diet (35 ppm Mn) was supplemented with 40, 80, or 120 ppm Mn from Manganese monoxide and fed ad libitum for 21 days.

Route of Administration: Oral

In Vitro Use Guide

Naked Manganese monoxide (MnO) nanoparticles had the cytototoxic effect with IC50 value more than 0.1 mg/ml in BRL 3A rat liver cells.

Substance Class	Chemical
Record UNII	Y40668X7G6
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

MANGANESE HYDROGEN CITRATE

Systematic Name

English

1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, MANGANESE(2+) SALT (1:1)

Preferred Name

English

MANGANESE (II) CITRATE

Systematic Name

English

MONOMANGANESE(II) CITRATE

Systematic Name

English

Showing 1 to 4 of 4 entries

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Show entries

Code System

Code

Type

Description

EPA CompTox

DTXSID40222047

PRIMARY

CAS

71799-92-3

PRIMARY

FDA UNII

Y40668X7G6

PRIMARY

PUBCHEM

14420749

PRIMARY

Showing 1 to 4 of 4 entries

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SMILES

InChI

CNS Activity

Originator

Approval Year

Targets

Conditions

PubMed

Patents

Sample Use Guides