DONIDALORSEN SODIUM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 01:44:11 GMT 2025` Edited by `admin` on `Wed Apr 02 01:44:11 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Type	COMPLETE
Record UNII	Y30VEG5PH1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DONIDALORSEN SODIUM

Official Name

English

ISIS-721744

Preferred Name

English

DONIDALORSEN SODIUM [USAN]

Common Name

English

ISIS721744

Code

English

ISIS 721744 [WHO-DD]

Common Name

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2- METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RA-SP- G-SP-T-SP-M5C-SP-T-SP-M5C-SP-T-SP-T-SP-G-SP-G-SP-M5C-SP-(2'-O-(2- METHOXYETHYL))RA-(2'-O-(2-METHOXYETH

Common Name

English

Code System Code Type Description

SMS_ID

300000028892

Created by admin on Wed Apr 02 01:44:11 GMT 2025 , Edited by admin on Wed Apr 02 01:44:11 GMT 2025

PRIMARY

FDA UNII

Y30VEG5PH1

Created by admin on Wed Apr 02 01:44:11 GMT 2025 , Edited by admin on Wed Apr 02 01:44:11 GMT 2025

PRIMARY

NCI_THESAURUS

C177098

Created by admin on Wed Apr 02 01:44:11 GMT 2025 , Edited by admin on Wed Apr 02 01:44:11 GMT 2025

PRIMARY

CAS

2304701-45-7

Created by admin on Wed Apr 02 01:44:11 GMT 2025 , Edited by admin on Wed Apr 02 01:44:11 GMT 2025

PRIMARY

USAN

HI-38

Created by admin on Wed Apr 02 01:44:11 GMT 2025 , Edited by admin on Wed Apr 02 01:44:11 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_3;1_6-1_16;1_19-1_20	15 / 19
	1_4-1_5;1_17-1_18	4 / 19

Related Record Type Details


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ACTIVE MOIETY

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