2'-FLUORO-2'-DEOXYURIDINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H11FN2O5
Molecular Weight	246.1924
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

InChIKey=UIYWFOZZIZEEKJ-XVFCMESISA-N

InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H11FN2O5
Molecular Weight	246.1924
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.	2005-12-15	16140016
Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.	2005-08-25	16107149
Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.	2005-03-01	15698782
Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe for thymidylate synthase.	2004-10-01	15475457

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:56:38 GMT 2025` Edited by `admin` on `Mon Mar 31 18:56:38 GMT 2025`
Record UNII	Y2YC903QW8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-(2-DEOXY-2-FLUORO-.BETA,-D-RIBOFURANOSYL)URACIL

Preferred Name

English

2'-FLUORO-2'-DEOXYURIDINE

Systematic Name

English

1-((2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL)PYRIMIDINE-2,4-DIONE

Systematic Name

English

URIDINE, 2'-DEOXY-2'-FLUORO-

Systematic Name

English

2'-DEOXY-2'-FLUOROURIDINE

Systematic Name

English

Code System Code Type Description

FDA UNII

Y2YC903QW8

Created by admin on Mon Mar 31 18:56:38 GMT 2025 , Edited by admin on Mon Mar 31 18:56:38 GMT 2025

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CAS

784-71-4

Created by admin on Mon Mar 31 18:56:38 GMT 2025 , Edited by admin on Mon Mar 31 18:56:38 GMT 2025

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EPA CompTox

DTXSID50999738

Created by admin on Mon Mar 31 18:56:38 GMT 2025 , Edited by admin on Mon Mar 31 18:56:38 GMT 2025

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PUBCHEM

150851

Created by admin on Mon Mar 31 18:56:38 GMT 2025 , Edited by admin on Mon Mar 31 18:56:38 GMT 2025

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