Raludotatug

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 09:53:03 GMT 2025` Edited by `admin` on `Wed Apr 02 09:53:03 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	Y2Y9AP91JZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1, anti-(human cadherin 6) (human-Rattus norvegicus monoclonal MABU-9014a ?1-chain), disulfide with human-Rattus norvegicus monoclonal MABU-9014a ?-chain, dimer

Preferred Name

English

Raludotatug

Official Name

English

raludotatug [INN]

Common Name

English

RALUDOTATUG [USAN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody

Common Name

English

gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-3*01 (86.7%) -(IGHD) -IGHJ4*01(93.3%), CDR-IMGT [8.8.15] (26-33.51-58.97-111))(1-122) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1R120 (219) (123-220), hinge 1-15 (221-235), CH2(236-345), CH3 E12 (

Common Name

English

Code System Code Type Description

FDA UNII

Y2Y9AP91JZ

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

PRIMARY

USAN

NO-02

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

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SMS_ID

300000046863

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

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INN

12315

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

PRIMARY

NCI_THESAURUS

C203045

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

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CAS

2610074-56-9

Created by admin on Wed Apr 02 09:53:03 GMT 2025 , Edited by admin on Wed Apr 02 09:53:03 GMT 2025

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From	To
4_133	4_193
4_23	4_88
3_133	3_193
3_23	3_88
2_372	2_430
2_266	2_326
2_225	4_213
2_149	2_205
2_22	2_96
1_372	1_430
1_266	1_326
1_234	2_234
1_231	2_231
1_225	3_213
1_149	1_205
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					U9G6UFV40X

TARGET->LIGAND

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_452] [2_452]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL