Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H6Cl4 |
| Molecular Weight | 291.988 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=C(Cl)C=C(C=C1)C2=CC(Cl)=C(Cl)C=C2
InChI
InChIKey=UQMGJOKDKOLIDP-UHFFFAOYSA-N
InChI=1S/C12H6Cl4/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6H
| Molecular Formula | C12H6Cl4 |
| Molecular Weight | 291.988 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006-11 |
|
| Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds. | 2006-08 |
|
| Evaluating the interactions of vertebrate receptors with persistent pollutants and antifouling pesticides using recombinant yeast assays. | 2006-07 |
|
| PCB congener-specific disruption of reproductive neuroendocrine function in Atlantic croaker. | 2006-07 |
|
| Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners. | 2006-05-25 |
|
| Differential effects of PCBs on the induction of apoptosis machinery and PKCalpha translocation in rat renal tubular cell cultures. | 2006-05-25 |
|
| Intestinal bioavailability and biotransformation of 3,3',4,4'-tetrachlorobiphenyl (CB 77) in in situ preparations of channel catfish following dietary induction of CYP1A. | 2006-04-20 |
|
| Comparison of hepatic and extra hepatic induction of cytochrome P4501A by graded doses of aryl hydrocarbon receptor agonists in Atlantic tomcod from two populations. | 2006-03-10 |
|
| Microbial reductive dechlorination of weathered and exogenous co-planar polychlorinated biphenyls (PCBs) in an anaerobic sediment of Venice Lagoon. | 2006-03 |
|
| Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation. | 2006-03 |
|
| Evaluating the role of desorption in bioavailability of sediment-associated contaminants using oligochaetes, semipermeable membrane devices and Tenax extraction. | 2006-03 |
|
| Characterization of the aryl hydrocarbon receptor repressor and a comparison of its expression in Atlantic tomcod from resistant and sensitive populations. | 2006-02 |
|
| Induction of cytochrome P4501A in African brown house snake (Lamprophis fuliginosus) primary hepatocytes. | 2006-02 |
|
| Selected polychlorobiphenyls congeners bind to estrogen receptor alpha in human umbilical vascular endothelial (HUVE) cells modulating angiogenesis. | 2006-01-20 |
|
| Effects of PCB 52 and PCB 77 on cell viability, [Ca(2+)](i) levels and membrane fluidity in mouse thymocytes. | 2006-01-16 |
|
| Gene expression patterns in estrogen (nonylphenol) and aryl hydrocarbon receptor agonists (PCB-77) interaction using rainbow trout (Oncorhynchus Mykiss) primary hepatocyte culture. | 2006-01-08 |
|
| Evidence of spatially extensive resistance to PCBs in an anadromous fish of the Hudson River. | 2006-01 |
|
| Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation. | 2005-12 |
|
| Neuropsychological effects of chronic low-dose exposure to polychlorinated biphenyls (PCBs): a cross-sectional study. | 2005-10-19 |
|
| Comparative sorption and desorption of benzo[a]pyrene and 3,4,3',4'-tetrachlorobiphenyl in natural lake water containing dissolved organic matter. | 2005-10-01 |
|
| Coplanar polychlorinated biphenyls activate the aryl hydrocarbon receptor in developing tissues of two TCDD-responsive lacZ mouse lines. | 2005-10 |
|
| Bioavailability of HOC depending on the colloidal state of humic substances: a case study with PCB-77 and Daphnia magna. | 2005-10 |
|
| The dioxin-like PCB 77 but not the ortho-substituted PCB 153 interferes with chicken embryo thyroid hormone homeostasis and delays hatching. | 2005-08 |
|
| EROD induction and PCDD/F levels in fish liver from the Biobio River in Chile. | 2005-08 |
|
| Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. | 2005-07 |
|
| Structural basis for preferential binding of non-ortho-substituted polychlorinated biphenyls by the monoclonal antibody S2B1. | 2005-05-10 |
|
| The contrasting roles of sedimentary plant-derived carbon and black carbon on sediment-spiked hydrophobic organic contaminant bioavailability to Diporeia species and Lumbriculus variegatus. | 2005-04 |
|
| Effects of 2,2',4,4'-tetrachlorobiphenyl on granulocytic HL-60 cell function and expression of cyclooxygenase-2. | 2005-04 |
|
| Uptake and tissue-specific distribution of selected polychlorinated biphenyls in developing chicken embryos. | 2005-03 |
|
| Exposure to PCB 77 affects the maternal behavior of rats. | 2005-01-31 |
|
| Effects of PCBs 52 and 77 on Th1/Th2 balance in mouse thymocyte cell cultures. | 2005 |
|
| Hippocampal long-term potentiation (LTP) is reduced by a coplanar PCB congener. | 2004-12 |
|
| Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats. | 2004-10-15 |
|
| Prior PCB exposure suppresses hypoxia-induced up-regulation of glycolytic enzymes in Fundulus heteroclitus. | 2004-10 |
|
| Interaction between halogenated aromatic compounds in the Ah receptor signal transduction pathway. | 2004-10 |
|
| Contrasting effects of coplanar versus non-coplanar PCB congeners on immunomodulation and CYP1A levels (determined using an adapted ELISA method) in the common sea star Asterias rubens L. | 2004-09-20 |
|
| Evidence for pi-pi electron donor-acceptor interactions between pi-donor aromatic compounds and pi-acceptor sites in soil organic matter through pH effects on sorption. | 2004-08-15 |
|
| Ortho-substituted PCBs kill cells by altering membrane structure. | 2004-07 |
|
| Biomarker responses in juvenile rainbow trout (Oncorhynchus mykiss) after single and combined exposure to low doses of cadmium, zinc, PCB77 and 17beta-oestradiol. | 2004-06-16 |
|
| Analysis of Ah receptor pathway activation by brominated flame retardants. | 2004-06 |
|
| Mechanochemical removal of organo-chlorinated compounds by inorganic components of soil. | 2004-06 |
|
| Ortho-substituted but not coplanar PCBs rapidly kill cerebellar granule cells. | 2004-05 |
|
| Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst. | 2004-04-08 |
|
| Effects of acute postnatal exposure to 3,3',4,4'-tetrachlorobiphenyl on sperm function and hormone levels in adult rats. | 2004-02 |
|
| Comparing behavioral and chronic endpoints to evaluate the response of Lumbriculus variegatus to 3,4,3',4'-tetrachlorobiphenyl sediment exposures. | 2004-01 |
|
| Effect of 3,4,3',4'-tetrachlorobiphenyl on the reworking behavior of Lumbriculus variegatus exposed to contaminated sediment. | 2004-01 |
|
| Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome p450 enzymes. | 2003-12-15 |
|
| Investigating the role of desorption on the bioavailability of sediment-associated 3,4,3',4'-tetrachlorobiphenyl in benthic invertebrates. | 2003-12 |
|
| Sediment characteristics affecting desorption kinetics of select PAH and PCB congeners for seven laboratory spiked sediments. | 2003-10-15 |
|
| Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice. | 2003-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:11:49 GMT 2025
by
admin
on
Mon Mar 31 19:11:49 GMT 2025
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| Record UNII |
Y2I6546TMI
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| Record Status |
Validated (UNII)
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| Record Version |
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36187
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DTXSID5022514
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