Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C28H50 |
| Molecular Weight | 386.6966 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)[C@@H](C)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChIKey=WAAWMJYYKITCGF-WTPIMUJOSA-N
InChI=1S/C28H50/c1-19(2)20(3)10-11-21(4)24-14-15-25-23-13-12-22-9-7-8-17-27(22,5)26(23)16-18-28(24,25)6/h19-26H,7-18H2,1-6H3/t20-,21+,22+,23-,24+,25-,26-,27-,28+/m0/s1
| Molecular Formula | C28H50 |
| Molecular Weight | 386.6966 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Regulation of cholesterol biosynthesis and metabolism in Hep G2 cells by delta8(14)-15-ketoergostane derivatives]. | 2011-01-25 |
|
| Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A. | 2010-12-02 |
|
| Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes. | 2010-12-02 |
|
| Methylantcinate A induces tumor specific growth inhibition in oral cancer cells via Bax-mediated mitochondrial apoptotic pathway. | 2010-10-15 |
|
| JBIR-14, a highly oxygenated ergostane, from Isaria sp. NBRC 104353. | 2010-03 |
|
| Antibacterial compounds from mushrooms II: lanostane triterpenoids and an ergostane steroid with activity against Bacillus cereus isolated from Fomitopsis pinicola. | 2010-03 |
|
| Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS). | 2010-01-29 |
|
| Steroidal lactones from Withania somnifera, an ancient plant for novel medicine. | 2009-07-03 |
|
| Cyclodextrin-modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata. | 2009-06 |
|
| [(22R,23R)-3beta-Hydroxy-22,23-epoxy-5alpha-ergost-8(14)-en-15-one: improved synthesis and toxicity to MCF-7 cells]. | 2008-12-18 |
|
| Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure. | 2008-11 |
|
| Brassinosteroids: synthesis and activity of some fluoro analogues. | 2008-07-10 |
|
| New anti-inflammatory ergostane-type ecdysteroids from the sclerotium of Polyporus umbellatus. | 2008-06-01 |
|
| Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera). | 2008-06 |
|
| Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C2-transfer activity. | 2008-03-20 |
|
| Anti-inflammatory ergostanes from the basidiomata of Antrodia salmonea. | 2007-09 |
|
| A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression. | 2007-05 |
|
| Selective cytotoxicity of withaphysalins in myeloid leukemia cell lines versus peripheral blood mononuclear cells. | 2006-09-27 |
|
| Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors. | 2005-09 |
|
| Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activity. | 2004-08 |
|
| Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. | 2004-02-18 |
|
| Byssochlamysol, a new antitumor steroid against IGF-1-dependent cells from Byssochlamys nivea. II. Physico-chemical properties and structure elucidation. | 2003-01 |
|
| Anicequol, a novel inhibitor for anchorage-independent growth of tumor cells from Penicillium aurantiogriseum Dierckx TP-F0213. | 2002-04 |
|
| Blazeispirols B, C, E and F, des-A-ergostane-type compounds, from the cultured mycelia of the fungus Agaricus blazei. | 2002-03 |
|
| New lanostanoids from the mushroom Ganoderma lucidum. | 2002-01 |
|
| [A comparative study on sterols of ethanol extract and water extract from Hericium erinaceus]. | 2001-12 |
|
| Cycloartanes, protolimonoids, a pregnane and a new ergostane from Trichilia reticulata. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:25:13 GMT 2025
by
admin
on
Mon Mar 31 22:25:13 GMT 2025
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| Record UNII |
Y0XC723P4C
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| Record Status |
Validated (UNII)
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| Record Version |
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164641
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Y0XC723P4C
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20652
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511-20-6
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m4984
Created by
admin on Mon Mar 31 22:25:13 GMT 2025 , Edited by admin on Mon Mar 31 22:25:13 GMT 2025
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PRIMARY | Merck Index | ||
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35512
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Ergostane
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admin on Mon Mar 31 22:25:13 GMT 2025 , Edited by admin on Mon Mar 31 22:25:13 GMT 2025
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